New decolonization method could lower infection risk in spine surgery
NCT ID NCT06633588
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This pilot study compares a new decolonization regimen using polyhexanide (nasal gel and body foam) to the standard mupirocin and chlorhexidine treatment for reducing Staphylococcus aureus bacteria before elective spine surgery. The trial includes 24 adults who carry Staph bacteria and are scheduled for spine surgery. The goal is to see if the new approach is feasible, tolerable, and effective at lowering bacterial levels to potentially prevent surgical infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- polyhexanide (nasal gel and body foam)
- What this could lead to
- If effective, this could offer an alternative decolonization method to reduce infection risk before spine surgery.
- What could go wrong
- This is a small pilot study with only 24 participants, so results may not be conclusive. The new regimen might not work as well as the standard treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Swiss Paraplegic Centre
Nottwil, Canton of Lucerne, 6207, Switzerland
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