Can tight BP control after pregnancy ward off heart disease?

NCT ID NCT05687344

Ongoing Disease control Sponsor: Medical College of Wisconsin Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study tests whether intensive blood pressure treatment after childbirth can improve women's long-term heart health. Researchers will enroll 60 women who had high blood pressure during pregnancy and give them nifedipine to keep their BP below 140/90 mmHg. The goal is to see if this approach is feasible and can reduce the risk of chronic hypertension and heart problems later in life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nifedipine (a blood pressure medication)
What this could lead to: If it works, this could show that tight blood pressure control after pregnancy reduces the risk of chronic hypertension and heart disease later in life.
What could go wrong: This is a small, early-phase feasibility study with only 60 participants, so results may not apply broadly. The intensive treatment may also cause side effects like dizziness or low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced hypertensive disorder preeclampsia Toxemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSIVE DISORDER OF PREGNANCY

Contacts and locations

Locations

Froedtert Hospital

Milwaukee, Wisconsin, 53226, United States

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