Simple supplement may shield First-Time moms from dangerous pregnancy hypertension
NCT ID NCT04979793
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether taking L-citrulline, a natural amino acid supplement, daily from early pregnancy can prevent high blood pressure conditions like preeclampsia in women expecting their first child. About 338 healthy first-time mothers between 12-16 weeks pregnant will receive either the supplement or a placebo. The trial is currently on hold, so results are pending.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- L-citrulline
- What this could lead to
- If it works, this could point toward a simple supplement to prevent pregnancy-related high blood pressure in first-time mothers.
- What could go wrong
- This is a very early Phase 1 trial, currently suspended, so results are far from certain. The supplement may not reduce blood pressure or may cause unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Texas Medical Branch
Galveston, Texas, 77555-0156, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Pregnancy complication linked to midlife brain changes?
- Can a common water pill keep blood pressure in check after childbirth?
- New app aims to keep moms-to-be with high blood pressure safer at home
- Phone apps may cut heart risk after pregnancy blood pressure problems
- Could a simple vitamin help pregnant women with high blood pressure?