Pregnancy disorder

This trial investigates whether screening for gestational diabetes earlier in pregnancy (at 18-20 weeks instead of the usual 24-28 weeks) and providing prompt lifestyle advice and medication if needed can reduce complications such as large babies, C-sections, and high blood press…

This study tested whether a 14-day course of hydrochlorothiazide (a water pill) could prevent high blood pressure from returning after delivery in women with preeclampsia or gestational hypertension. Over 450 women were planned, but the trial was stopped early. The main goals wer…

This study tested an early speech therapy program for children born very prematurely or with severe growth restriction. The program involved 10 to 20 sessions with a trained speech therapist from 6 to 24 months of age. The goal was to see if it could reduce language and communica…

This study tested an experimental drug called AMAG-423 (Digoxin Immune Fab) in pregnant women with severe preeclampsia, a dangerous condition of high blood pressure during pregnancy. The goal was to see if the drug could reduce serious health problems in babies, such as bleeding …

This study tested a community-based program called Meals 4 Moms for pregnant women with gestational diabetes. Participants received tailored meals, education, and activity monitoring. The goal was to see if the program was practical and acceptable. Only 8 women were enrolled befo…

This study looked at two ways of giving growth hormone to short children who were born small for their age. The goal was to see which dosing method works better for growth and has fewer side effects on metabolism. Only 10 children took part before the study was stopped early.

This study tested a new way to manage blood pressure in new mothers with severe postpartum preeclampsia. Participants received standard blood pressure medications, but one group had personalized blood pressure targets based on real-time brain monitoring. The goal was to keep bloo…

This study tested whether placing cold, wet sponges on the uterus during a cesarean delivery could help it contract better, reducing blood loss and the need for extra drugs or a hysterectomy. Only 8 women participated before the trial was stopped early. The results are too limite…

This study aimed to see if the CONNEQT Pulse blood pressure monitor gives accurate readings in pregnant women, including those with high blood pressure or pre-eclampsia. Researchers compared it to a standard blood pressure cuff in 41 pregnant volunteers. The study was stopped ear…

This study looked at whether a third-trimester ultrasound can accurately find bowel rotation issues in fetuses that raise the risk of a life-threatening twist (volvulus). Researchers compared ultrasound results with fetal MRI, the current best method. The study included 77 pregna…

This study tested whether the cholesterol-lowering drug pravastatin could prevent preeclampsia in women who had a previous early preterm delivery due to the condition. The trial planned to enroll 1,550 women but was terminated early with only 102 participants. Because it stopped …

This study aimed to compare two blood pressure medications—oral nifedipine (a pill) and intravenous labetalol (given through a vein)—for treating dangerously high blood pressure in women who have just given birth. The goal was to see which drug lowers blood pressure faster. Howev…

This study looked at whether slow, deep breathing for 10 minutes daily could help lower blood pressure in pregnant women with pregnancy-induced hypertension. Only 1 participant was enrolled before the study was terminated, so no meaningful conclusions can be drawn. The goal was t…

This study tested a virtual reality training program for maternity care providers, nurses, lactation consultants, and doulas. The goal was to improve teamwork and reduce pain disparities for birthing parents. The study enrolled 66 participants but was terminated early, so the res…

This study looked at how aware pregnant women in Norway are about oral health and how their attitudes affect cavity risk. Researchers gave 97 women information on dental care to see if it improved their oral bacteria and reduced cavities. The study aimed to understand if better g…

This study aimed to find the best time (between 37 and 39 weeks of pregnancy) to deliver babies of women with poorly controlled gestational diabetes. Researchers planned to enroll up to 3,450 pregnant women but stopped early with 304 participants. The goal was to see which delive…

This pilot study tested whether semi-permanent acupuncture could reduce the need for medical induction of labor in pregnant women at low or moderate risk. Only 8 women participated before the trial was terminated early. The goal was to see if this approach is feasible and to plan…

This study looked at whether certain genetic variations (SNPs) in cholesterol-related genes (LXRs) are linked to difficult labor (dystocia) that requires a C-section. Researchers planned to analyze blood samples from 58 women having C-sections due to stalled labor. The study was …

This study tested a non-invasive blood pressure monitor (CNAP) against the standard invasive method (using a needle in the artery) in 20 pregnant women with placenta accreta undergoing scheduled C-sections. The goal was to see if the gentler method gives equally accurate readings…