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Pill vs. IV: which works faster for postpartum hypertension?

NCT ID NCT05139238

Terminated Symptom relief Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to compare two blood pressure medications—oral nifedipine (a pill) and intravenous labetalol (given through a vein)—for treating dangerously high blood pressure in women who have just given birth. The goal was to see which drug lowers blood pressure faster. However, the trial was stopped early after only 2 participants enrolled, so no meaningful results were obtained.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nifedipine and labetalol
What this could lead to
If it worked, this could show that a simple pill works as well as an IV drug for treating severe postpartum high blood pressure, making treatment easier and faster.
What could go wrong
The trial was terminated after enrolling only 2 people, so no reliable conclusions can be drawn. It is too small to know which drug is better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced Hypertensive Crisis hypertensive disorder malignant hypertension preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSIVE EMERGENCY POSTPARTUM PREECLAMPSIA POSTPARTUM PREGNANCY-INDUCED HYPERTENSION PREGNANCY-INDUCED HYPERTENSION IN POSTPARTUM

Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.