Diabetes drug metformin tested to prevent deadly pregnancy complication
NCT ID NCT03570632
First seen Jan 09, 2026 · Last updated Jun 22, 2026 · Updated 25 times
Summary
This phase 4 trial tests whether the diabetes drug metformin can prevent preeclampsia (a dangerous pregnancy complication) in pregnant women with type 1 diabetes. About 60 women will receive either metformin or standard care starting before 20 weeks of pregnancy. Researchers will track rates of high blood pressure disorders and other outcomes to see if metformin offers protection.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETES MELLITUS, TYPE 1 are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Magee Womens Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin
What this could lead to
If it works, this could point toward a safe way to prevent dangerous pregnancy complications in women with type 1 diabetes.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Metformin may not reduce preeclampsia risk as hoped.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.