The University Of Hong Kong

This study looks at whether different exercise programs can help older adults stay healthy and active. About 1940 people aged 60 and older will be assigned to one of several exercise groups or a no-exercise control group. Researchers will measure physical abilities, mental well-b…

This study is testing a new way to help women reduce their alcohol use. Participants will get brief counseling, daily check-ins via a phone app, and join a private social media support group. The goal is to see if this approach is practical and helpful for women who are at-risk d…

This study looks at the best time to restart blood thinners (DOACs) after having polyps removed during a colonoscopy. About 194 adults who take these medications will be randomly assigned to restart them either the same day or two days later. The goal is to see if restarting earl…

This small pilot study is testing whether electrical stimulation of the spinal cord can help people with long-term spinal cord injury regain movement and function. Five participants will receive a spinal cord stimulator implant and go through three phases: stimulation of the lowe…

This study tests a health chat program (HcELP_CMM) for adults with two or more heart-related conditions like high blood pressure, diabetes, or heart disease. The program uses a chat app to help people set lifestyle goals and track progress. Researchers want to see if it's easy to…

This study tests whether a device called PTeye™ can reduce the risk of low calcium levels after total thyroid removal. About 210 adults having thyroid surgery in Hong Kong will be randomly assigned to either standard surgery or surgery with the probe. The probe helps surgeons see…

This study looks at whether artificial intelligence (AI) can give personalized tooth-brushing and flossing advice as effectively as a dentist for people with prediabetes. The goal is to reduce gum inflammation and potentially improve blood sugar levels. About 148 adults with pred…

This study tests a program to help smoking parents quit by combining brief advice, nicotine replacement therapy (like patches or gum), and support through instant messaging. The goal is to help parents stop smoking and reduce their children's exposure to secondhand smoke. The stu…

This study tests whether using a Fitbit alone or with health coaching helps adults aged 40+ with belly fat move more and improve heart health. 133 participants will be split into three groups: one gets a Fitbit with special features, another gets the Fitbit plus coaching, and a c…

This study tests a new approach for people with liver cancer that cannot be removed by surgery. The treatment combines immunotherapy (which helps the immune system fight cancer) with targeted radiation to shrink the tumor enough so it can be surgically removed. The goal is to see…

This study tests if a mobile health app can help people who had a bleeding stroke better control their blood pressure. About 140 participants will use the app to track their numbers and get health tips. The goal is to see if the app helps more people reach safe blood pressure lev…

This study tests whether using a special score (TRICH score) to decide who gets a triple blood pressure pill soon after a brain bleed stroke leads to better blood pressure control. About 140 adults in Hong Kong who had a brain bleed and have a high TRICH score will take either th…

This study tests whether a combination of two drugs (levonorgestrel and piroxicam) works better than the standard emergency contraceptive ulipristal acetate at preventing pregnancy. About 980 women aged 18-45 who need emergency contraception within 5 days of unprotected sex will …

This study tests whether adding diquafosol eye drops to standard treatment helps people with moderate-to-severe vernal keratoconjunctivitis (a serious eye allergy). About 94 participants aged 6 and older will receive either diquafosol plus cyclosporine or cyclosporine alone. Rese…

This study tests whether chat-based text messaging and online education hubs can help Hong Kong teens aged 12-18 reduce how often they drink alcohol and binge drink. About 100 teens who have had alcohol in the past year will use WhatsApp and online materials. Researchers will tra…

This study tests a new way to deliver chemotherapy called PIPAC, which sprays chemo directly into the abdomen as a fine mist. It is for people with stomach, pancreatic, or colorectal cancer that has spread to the lining of the abdomen. The goal is to see if this approach can cont…

This study tests whether the drug tranexamic acid can prevent bleeding from expanding in the brain after a hemorrhage. The trial enrolls 70 adults with a specific type of brain bleed, using tailored volume criteria to select those most likely to benefit. The goal is to reduce ear…

This study looks at whether using a hormone drug called GnRH agonist can help more women have a baby through IVF and frozen embryo transfers. About 784 women under 43 will be split into groups to compare this drug against the standard hCG trigger. The goal is to see if the new ap…

This study tests a tailored lifestyle program for 152 Chinese adults with metabolic syndrome, a cluster of conditions like high blood pressure and blood sugar. Participants receive either the program or brief advice, with health changes measured over 20 weeks. The goal is to see …

This study is testing an artificial intelligence (AI) system to help doctors diagnose spinal deformities like scoliosis. Researchers will collect X-rays from 2,500 people with spine conditions and see if the AI can measure spinal curves as accurately as a human expert. The goal i…

This study aims to create a simple, fast test (like a pregnancy test) to detect poisonous substances from certain Chinese herbs (aconite) in urine. Current lab tests take too long, delaying treatment. Researchers will test the accuracy of this new device in 90 adults who may have…

This study compares AI-assisted upper endoscopy with standard high-definition endoscopy to see which misses fewer stomach growths (neoplasms). About 1000 adults aged 40 or older scheduled for an elective endoscopy will be randomly assigned to one of the two methods. The goal is t…

This study aims to create a simple, non-invasive test to detect early signs of poor balance and coordination in people with degenerative cervical myelopathy (DCM), a spinal cord condition. Researchers will enroll 100 Chinese adults aged 50 and older who have evidence of DCM. By u…

This study tests whether a portable electronic stethoscope, combined with machine learning, can accurately detect valvular heart disease. About 125 people with and without the condition will take part. Their heart sounds will be recorded and compared to standard tests like echoca…

This study is testing whether low-dose CT scans can find lung cancer early in people aged 50 to 75 who have a parent, sibling, or child with lung cancer. Unlike most screening programs that focus on heavy smokers, this study also includes non-smokers. The goal is to see if family…

This study tests whether a single injection of a GLP-1 drug (dulaglutide), given 1 to 14 days before planned non-cardiac surgery, can reduce heart muscle injury in 372 adults at risk. Participants are randomly assigned to receive the drug or standard care. The goal is to see if t…

This study tests an 18-week sport stacking program for people with mild dementia and their family caregivers. The program includes online group sessions and home practice to improve thinking, mood, and quality of life. Researchers will compare results to a group receiving basic d…

This study tests a 16-week partner exercise program for people with mild dementia and their family caregivers. The goal is to see if exercising together improves thinking, mood, and the relationship between them. About 236 pairs will join from community centers in Hong Kong.

This study tests whether a 14-week elastic band exercise program can improve muscle mass, strength, and physical function in older adults with heart failure who also have sarcopenia (age-related muscle loss). Researchers will enroll 62 participants aged 50 and older to see if thi…

This study tests a personalized therapy delivered by instant message to help people with mild cognitive impairment manage mood and behavior symptoms. Researchers will enroll 160 adults aged 50 and older who have early memory problems but not dementia. The therapy aims to reduce s…

This study tests a group-based program for families of individuals with special health care needs. The program focuses on promoting psychological flexibility and value-guided living rather than changing distressing thoughts. Researchers will measure changes in stress, well-being,…

This study tests if narrative therapy—a type of counseling where people explore their personal stories—can reduce mental distress, depression, and anxiety in young people. About 770 at-risk youth in Hong Kong, ages 12 to 24, will take part. They will attend six face-to-face sessi…

This study aims to find and support hidden caregivers—people who care for an older adult but don't use respite services. Caregivers are assessed and then receive services matched to their needs. The goal is to improve their mental well-being, social connections, and quality of li…

This study tests an internet-based self-help program called eConquerFear-HK for Chinese cancer survivors who have mild to moderate fear of their cancer coming back. About 48 people who finished treatment for early-stage breast or colorectal cancer will try the program. The goal i…

This study tests a personalized strength exercise program for older adults (60+) who are at risk of losing physical function after a hospital stay. Participants do tailored exercises at home, and researchers measure improvements in mobility, balance, and frailty. The goal is to h…

This study tests a 12-week program called ENACT for people with mild cognitive impairment (mild memory problems) and hearing loss. The program combines hearing exercises, thinking games, and support from nurses, peers, and family. Researchers want to see if it improves memory, at…

This study tests whether a nurse-supported mobile app that teaches healthy sleep habits can reduce insomnia in people caring for a family member or friend with cancer. About 208 caregivers will either use the app for 6 weeks with weekly nurse check-ins or receive basic sleep tips…

This study tests three different doses of a long-acting numbing medicine (liposomal bupivacaine) injected into a nerve block in the thigh to control pain after total knee replacement. About 177 adults having robotic knee surgery will be randomly assigned to receive one of the dos…

This study tests whether pairing a non-invasive brain stimulation technique (rTMS) with a computer-based thinking exercise can reduce negative thought patterns and mild-to-moderate depression symptoms. About 180 adults with depression will receive either real or fake rTMS, combin…

This study tests a parent-led sleep program delivered online for children aged 6–12 with autism and insomnia. Researchers want to see if it improves the child's sleep, daytime behavior, and autism symptoms, as well as parents' sleep and stress. About 195 families will take part, …

This study tests whether showing children a real-time ultrasound image of their tongue movements can help them learn to pronounce sounds correctly. Sixty children with speech sound disorders will be randomly assigned to receive this extra visual feedback during speech therapy or …

This study tests whether a non-invasive brain stimulation technique called rTMS, followed by intensive arm training, can reduce muscle stiffness (spasticity) in children aged 7–18 with hemiplegic cerebral palsy. Twenty participants will receive either real or sham rTMS over 10 da…

This study tests a new risk model designed to predict severe side effects from cancer treatments in people aged 65 and older. Participants will either receive usual care or have their treatment plan adjusted based on their risk level, with closer monitoring for those at higher ri…

This study tests a 6-week WeChat-based group program called SOCIAL_HF for elderly people with heart failure who feel socially frail. Participants join weekly video chats, do tasks, and access resources. Researchers want to see if this improves social connections, self-care, and s…

This study tests if a non-invasive brain stimulation technique called tDCS can help young adults (18-35) with mild depression feel better. Participants will receive either real tDCS or a sham (fake) treatment for 10 sessions over 2 weeks. Researchers will track mood changes for u…

This study tests a new program called Mindful-Breath for people with COPD. It combines mindfulness, exercise training, and lifestyle advice delivered through group sessions and text messages. The goal is to see if this approach is practical and helps reduce stress and improve phy…

This study tests if acupressure can reduce coughing and related symptoms like shortness of breath and fatigue in people who have had lung cancer. Eighty participants will either receive acupressure for 8 weeks or get an education booklet. The goal is to see if acupressure improve…

This study tests a program called BrainLive Connect, where trained volunteers lead fun mental activities for people with mild to moderate dementia. The goal is to see if these sessions, held over 7 weeks, can improve thinking skills and quality of life compared to usual care. Abo…

This study tests a chatbot called Digi-Coach to see if it can reduce physical and emotional distress in people receiving radiotherapy for head and neck cancer. About 138 adults will either use the chatbot alongside standard nursing care or receive usual care alone. The goal is to…

This study tests whether a non-invasive radiofrequency treatment, combined with meibomian gland expression, can improve tear film stability and reduce dry eye symptoms better than gland expression alone. About 112 adults with moderate-to-severe meibomian gland dysfunction that ha…

This pilot study tests whether high-dose vitamin D can help the body clear blood from the brain after a hemorrhagic stroke. Researchers will give 40 participants either vitamin D or standard care for 26 weeks. The goal is to see if vitamin D is safe and speeds up recovery.

This study tests whether a chatbot powered by large language models can help people with metabolic alcohol-related liver disease (MetALD) reduce their alcohol intake. About 50 adults in Hong Kong will use the chatbot for counseling. The main goal is to see if the approach is prac…

This study tests whether the drug vericiguat can improve blood flow in the tiny vessels of the heart and reduce chest pain. About 94 adults aged 40-75 with stable chest pain but no major blockages will take the drug or a placebo. The main goal is to see if heart blood flow improv…

This study tests a program called COPE for people caring for a loved one with dementia. The program combines in-person and online sessions to help caregivers reduce stress, depression, and negative feelings toward the person they care for. About 56 caregivers will take part, and …

This study tests whether eight weeks of mindfulness training, done together by a person with Parkinson's disease and their family caregiver, can reduce negative emotions like stress, anxiety, and depression. About 200 patient-caregiver pairs will either take the mindfulness class…

This study compares a nurse-led mind-body program (like gentle movement and breathing) to friendly conversation sessions for reducing loneliness in older adults living in long-term care homes. About 120 residents aged 60 and older who can speak Cantonese will take part. The goal …

This study looks at whether music therapy can improve mental health and social connections in university students who feel stressed, anxious, or depressed. Twenty students aged 18-40 with moderate symptoms will be randomly assigned to either four individual music therapy sessions…

This study tests if a type of talk therapy for insomnia (CBT-I) can also reduce impulsive behavior and risk-taking in young people aged 12 to 24. Researchers will compare changes in impulsivity and sleep quality between those who receive the therapy and those who do not. The goal…

This study tests whether a special story, read in class, can help young children with autism feel less scared and more cooperative during dental checkups. About 106 preschool children in Hong Kong will either get the dental story or a general story, and researchers will measure h…

This study tests a new AI tool that helps surgeons find tiny blood vessels (called skin perforators) needed for a type of reconstructive surgery using a bone and skin flap from the leg. About 49 adults who need this surgery will have their CT scans analyzed by the AI, and the res…

This study tests whether using a life history calendar—a simple grid that helps people remember important life events—can improve how accurately adults in Hong Kong recall and report mental health conditions like depression, anxiety, and PTSD. Researchers will compare the standar…

This study aims to develop new criteria using simple physical tests—like how many times you can grip and release your hand in 10 seconds—to help decide when surgery is needed for degenerative cervical myelopathy, a condition that compresses the spinal cord in older adults. Resear…

This study is looking for new ways to quickly and accurately diagnose strokes using blood and saliva tests. Researchers will study 650 adults who come to the emergency room with stroke symptoms. The goal is to find markers that can tell if a stroke is happening, what type it is, …

This study tests whether a specially designed game can help adults who have gone through major life stress feel more positive and resilient. Sixty participants will be split into three groups: one plays the game, one gets standard mental health education, and one waits. Researche…

This study looks at whether experiencing awe—like seeing a beautiful sunset—can make people more willing to help prevent infectious diseases. Researchers will ask 456 adults from Hong Kong, Singapore, and major Chinese cities about their intentions to get vaccinated, wear masks, …

This study looks at whether a special training program for volunteers aged 50 and over can improve their knowledge about dementia and their own wellbeing. About 180 volunteers in Hong Kong will either take the training or just receive educational materials. Researchers will compa…

This study tests whether a nurse and allergist working together can safely and effectively remove incorrect penicillin allergy labels from patients' records. About 440 people with a penicillin allergy label will be evaluated using this team approach or the standard allergist-only…

This study is enrolling 2000 adults who come to the emergency department with a suspected respiratory infection. Researchers will collect blood and other samples to build a biobank and analyze the body's response to different germs. The goal is to discover better ways to diagnose…

This study follows 404 people who previously had a colonoscopy, either with or without AI help, to see if AI reduces the chance of developing advanced colon polyps later. Participants will get a follow-up colonoscopy to check for new growths. The goal is to learn if AI can improv…

This study tests a program called Project ReBond that provides counseling, job help, and other support to people serving their first or second prison sentence in Hong Kong. The goal is to see if this extra help reduces the chance of reoffending after they are released. The study …

This study tests whether a smartphone app (DigitHeart-2) can accurately predict heart structure and function from a simple ECG picture. About 478 adults who need an echocardiogram will have their ECG photo analyzed by the app, and the results will be compared to the standard ultr…

This study tests a new version of a mental health interview called the CIDI 5.0. Researchers want to see if it correctly identifies people who have had depression, anxiety, or PTSD at some point in their lives. About 300 adults in Hong Kong will take the CIDI 5.0 and then a more …

This study looks at whether exercise, like walking and telehealth coaching, along with smoking cessation advice, can improve the lung function of smokers who already have early signs of lung trouble. Researchers will track 90 adults for a year to see if these steps help prevent c…

This study looks at whether a program called REACH & Map can help older adults who are hard to reach (age 60+) improve their physical health, memory, mood, and social connections. Researchers will track 5,500 participants in Hong Kong using surveys and tests. The goal is to see i…

This study tests a 14-week program called Path-HA designed to help older adults (60+) who are at risk of aging faster than normal. The program includes health education and support to improve quality of life, strength, and balance. 1000 participants will be randomly assigned to e…