Could a common painkiller boost emergency contraception? new trial tests combo pill

NCT ID NCT06727734

Recruiting now Disease control Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of levonorgestrel (a hormone) and piroxicam (an anti-inflammatory drug) works better than the standard emergency contraceptive ulipristal acetate. About 980 women will take a single dose of either the combo or the standard pill, then be followed for up to 6 weeks to see who becomes pregnant. The goal is to find a more effective way to prevent pregnancy after unprotected sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Levonorgestrel and piroxicam combination
What this could lead to: If successful, this could offer a more effective emergency contraception option than the current standard ulipristal acetate.
What could go wrong: This is a Phase 3 trial, but results may not show a clear advantage. Side effects like menstrual changes or drug interactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONTRACEPTION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

The Family Planning Association of Hong Kong
RECRUITING

Hong Kong, Hong Kong

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

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