Could a single implant replace the morning-after pill?

NCT ID NCT05237141

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study tests whether inserting the etonogestrel contraceptive implant before ovulation can prevent pregnancy, potentially serving as emergency contraception. Twelve women with regular cycles will receive the implant when their dominant follicle reaches a certain size but before the hormone surge that triggers ovulation. Researchers will track hormone levels and ultrasound images to see if ovulation is blocked. If successful, this could offer a longer-acting emergency contraceptive option and simplify birth control access.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Etonogestrel implant
What this could lead to
If it works, this could allow the etonogestrel implant to be used as emergency contraception, simplifying birth control access and reducing the need for extra emergency pills.
What could go wrong
This is a small pilot study with only 12 participants, so results may not apply broadly. The implant may not reliably block ovulation in all cases, and more research would be needed before changing guidelines.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Denver

    RECRUITING

    Aurora, Colorado, 80045, United States

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