DEMENTIA

This study tested a one-year virtual program for people with dementia and their caregivers. Nearly 1,000 participants received monthly video or phone visits with a nurse or social worker who helped manage symptoms, medications, and caregiver stress. The goal was to reduce emergen…

This study looked at whether two different blood thinners—dabigatran and warfarin—could help prevent dementia and memory loss in people over 65 with atrial fibrillation (an irregular heartbeat). About 100 participants were followed for two years with memory tests and brain scans.…

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's disease who also had signs of brain inflammation. The goal was to see if the drug could improve thinking, memory, and daily function compared to a placebo over 24 weeks. The study also che…

This study looked at whether a blood test can accurately diagnose Alzheimer's disease, instead of the usual spinal fluid test. Researchers tested 342 adults visiting memory clinics. They measured certain proteins in the blood and compared results to standard diagnostic methods. T…

This study tested a simple, low-cost method to find undiagnosed dementia in older adults by analyzing electronic health records. Over 1,200 participants without a prior dementia diagnosis took part. The goal was to see if the eRADAR algorithm could help doctors detect dementia ea…

This study tested whether an AI tool that analyzes speech can help detect early signs of dementia or mild cognitive impairment. Researchers recorded the speech of 273 adults aged 55 and older, including healthy volunteers and those with memory concerns. The goal was to see if cha…

This study looked at whether a blood test can help diagnose Alzheimer's disease. Researchers measured two specific proteins in the blood of 200 people (some with Alzheimer's, some healthy) to see if the test could tell the difference. The goal is to create a simpler, less invasiv…

This study tested a new blood test that uses a special chip to look for Alzheimer's-related markers in red blood cells. Researchers compared results from 50 people with Alzheimer's, 50 with other brain diseases, and 50 healthy adults. The goal is to create a simple, non-invasive …

This study tested whether an 8-week course taught by a robot could help prevent or delay cognitive decline in older adults with mild memory problems. 80 people aged 65 and older took part, with half attending robot-led classes and the other half receiving no intervention. The pro…

This study tested a medicine called BXCL501 for calming sudden episodes of agitation in people with dementia. 151 participants took the medicine as needed over 12 weeks. The goal was to see if it safely reduces symptoms like tension and hostility.

This study tested a web-based app called Gotcha! that helps people with mild-to-moderate dementia practice remembering names of people they know. 48 participants used the app at home for about 30 minutes each day over 6 weeks. The goal was to see if the app could improve name rec…

This study looked at whether a long-term exercise program can help people with dementia living in nursing homes maintain their ability to do daily tasks like bathing and dressing. 140 participants were split into an exercise group and a social activity group. The goal was to see …

This study tested a video-based program called Tele-STELLA that helps family caregivers of people with Alzheimer's or related dementias. The program connects caregivers with a guide to find ways to reduce upsetting behaviors in their loved ones. The goal was to lower caregiver st…

This pilot study tested whether adding horse therapy to memory workshops helps people with mild to moderate dementia. 36 older adults took part in either horse-assisted memory workshops, traditional memory workshops, or a control group. Researchers measured changes in thinking, m…

This study looked at whether listening to emotionally meaningful music can improve mood and alertness in people with moderate to severe Alzheimer's disease. Ten participants were exposed to special music and a control condition. Researchers measured changes in overall well-being …

This study looked at how visits from therapy animals affect people with moderate to severe dementia living in nursing homes. Researchers observed changes in mood, behavior, and communication during animal visits compared to other activities. The goal was to see if animal-assisted…

This study tested a distance-learning program that trains family caregivers to reduce care-resistant behaviors (like agitation or aggression) in people with Alzheimer's dementia or traumatic brain injury. About 88 participants and their unpaid caregivers took part. The goal was t…

This study tested a gamified assistive technology (MapHabit) in 40 people with mild-to-moderate Alzheimer's or related dementias and their primary caregivers. Over 6 months, one group used the gamified version while the control group used the standard app. The goal was to see if …

This study tested a mobile app designed to help people caring for a loved one with dementia. The app provided training and support to reduce caregiver burden and improve quality of life. 75 caregivers participated, with half using the app for two months and the other half receivi…

This study tested new exercises to help people with Alzheimer's and related dementias who have trouble swallowing. The goal was to reduce leftover food in the throat after swallowing, which can lead to pneumonia. 76 patients and their caregivers took part. Researchers measured ch…

This study tested a hearing program delivered by a speech-language pathologist for older adults with both hearing loss and dementia. The goal was to see if improving hearing access could reduce troubling symptoms like agitation or mood changes. 77 people with mild to moderate dem…

This study tested different doses of nicotinamide riboside (NR), a vitamin B3-like supplement, in 80 people with early Alzheimer's disease. The goal was to find the best dose that increases brain energy levels and changes brain metabolism safely. Participants took placebo or NR d…

This study tested whether using adult day services (like adult daycare) can lower stress in Black caregivers of family members with dementia. 42 caregivers who used these services at least twice a week took part. Researchers measured stress through surveys and saliva samples to s…

This study tested a program called Shed-MEDS that helps people with dementia living in assisted living facilities safely stop or reduce unnecessary or harmful medications. The goal was to improve quality of life by reducing the number of drugs they take. Researchers worked with 1…

This study tested a home-based device called Care4AD to help caregivers of people with Alzheimer's or dementia. The goal was to see if it could reduce caregiver burden and stress over 3 months. The study involved 33 caregivers and older adults with mild to moderate dementia. The …

This study tested a tablet-based exercise program called KOKU-LITE, designed to help people with dementia improve their balance and prevent falls. 60 people with dementia and their carers took part. The goal was to see if the program was easy to use and could improve quality of l…

This study tested a structured oral health care program for older adults (60+) with dementia at a day care center. Over 4 weeks, the program aimed to improve oral hygiene and mouth function. Researchers measured plaque, tongue coating, and overall oral health to see if the progra…

This study tested whether a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) could improve memory and thinking in 32 veterans aged 55+ with mild cognitive impairment or early dementia. Participants received rTMS sessions, and researchers measured …

This study tested whether combining acupuncture and acupressure can improve memory and daily life for elderly people with mild to moderate dementia. 236 people aged 65 and older from nursing homes took part. They received either routine care, acupuncture, acupressure, or both for…

This study tested a gentle nerve stimulation device worn on the ear to see if it could improve thinking, sleep, and reduce inflammation in older adults with frailty. 80 people over age 60 without dementia took part. Half received the real stimulation and half received a sham (fak…

This study tested a program called IPPI for 108 nursing home residents with dementia and depression. Care partners offered two short, personalized activities each week for six months. The goal was to see if this approach could improve mood and reduce distressing behaviors. The st…

This study tested an online workshop for 109 family caregivers of people with dementia. The workshop taught caregiving skills and ways to manage stress and difficult emotions. The goal was to see if the workshop was feasible and helpful for caregivers, with the long-term aim of i…

This study tested a program called MEMORI Corps, where trained volunteers aged 55+ spend time with people who have dementia, doing activities they enjoy. The goal was to see if this companionship could reduce loneliness and improve quality of life for the person with dementia, wh…

This study tested a support program for people with dementia living at home. Nurses were trained to focus on what the person still wants and can do, rather than taking over tasks. The program included home conversations with the person and their family caregiver to agree on what …

This study tested whether weighted blankets can reduce agitation and other behavioral symptoms in people with dementia. Thirty patients from hospital and hospice settings participated. Researchers measured changes in agitation and overall symptom burden using standard scales. The…

This study tested whether structured music improvisation sessions led by professional musicians could improve the mental and physical health of older adults with dementia. Seven participants aged 60 and older with mild to moderate dementia took part, along with their caregivers. …

This study tested a new in-home technology designed to help Spanish-speaking caregivers of people with Alzheimer's, dementia, or mild cognitive impairment. The goal was to see if the system could reduce caregiver anxiety, burden, and loneliness. Six caregivers used the technology…

This study tested an online tool called WeCareAdvisor that helps caregivers of people with dementia manage difficult behaviors like aggression or wandering. 262 caregivers used the tool to see if it reduced their stress and boosted their confidence. The goal was to make daily car…

This study tested whether methylphenidate (Ritalin), a drug used for ADHD, could improve walking problems and attention in people with advanced Parkinson's disease. 69 participants with severe gait issues and freezing episodes were given either the drug or a placebo for 3 months.…

This study tested whether giving dementia patients a robotic pet (like a robotic cat or dog) during their hospital stay could improve their well-being and reduce problems like confusion, falls, and the need for strong medications. 106 adults aged 65 and older with mild-to-moderat…

This study tested an upgraded smart cloth home care system with a family caregiver app for people with dementia. 60 people with dementia and their family caregivers in Northern Taiwan took part. The goal was to see if the system could improve caregiver preparedness, reduce depres…

This study tested a personalized activity plan for 61 people with early-stage dementia. The goal was to see if meaningful activities could improve thinking, memory, and mood. Researchers worked directly with participants to design activities that could adapt as the disease progre…

This study tested whether a digital cognitive behavioral therapy program for insomnia (Sleepio) is practical and helpful for people aged 50+ with mild cognitive impairment or mild dementia who also have sleep problems. Thirty participants were enrolled to see if they would stick …

This study tested whether digital or physical brain games can improve thinking, mood, and quality of life in 514 older adults with mild-to-moderate Alzheimer's disease. Participants did one-on-one cognitive stimulation activities, either on a computer or with traditional material…

This study tested whether special snacks that change texture in the mouth could help improve nutrition in people with dementia. Ten adults with dementia living at home tried these snacks for several weeks. The goal was to see if the snacks were safe, easy to use, and liked by par…

This study tested a virtual group therapy program called Cognitive Stimulation Therapy (V-CST) for people with mild to moderate dementia. 133 participants were randomly assigned to either join the online therapy or receive usual care. The goal was to see if the therapy could slow…

This study tested a special palliative care program for people with late-stage Alzheimer's or related dementias and their family caregivers. The program started during a hospital stay and included dementia-specific comfort care, caregiver education, and help with transitions. The…

This study tested whether a virtual reality program that shows nostalgic scenes (like old neighborhoods or festivals) could improve emotional well-being and thinking skills in older adults with mild memory problems. Sixty-four people aged 65 and older took part, using VR twice a …

This study tested a program called Care Ecosystem, which provides dementia care support over the phone and internet. Over 1,200 people with dementia and their caregivers took part across six health systems. The program aimed to improve quality of life, reduce emergency room visit…

This study tested an online platform called LifeBio Memory that helps people with dementia and their caregivers share and record life stories. The platform uses machine learning to turn speech into text, making it easier to create personalized life story materials. 234 residents,…

This study tested a safe, non-invasive brain stimulation device that people with mild to moderate Alzheimer's used at home for 30 minutes a day, five days a week, for six months. The goal was to see if it could improve thinking, memory, and daily function. One hundred older adult…

This study tested whether wearable devices like Apple Watches could help reduce anxiety, burden, and loneliness in people caring for a spouse or family member with dementia or mild cognitive impairment. 63 caregivers in the U.S. used the technology for 6 months. The goal was to s…

This study tested whether playing digital games in a group twice a week for 20 weeks could improve thinking, mood, and behavior in 24 older adults with early to moderate dementia. Researchers measured changes using standard tests for memory and mood. The goal was to see if this e…

This study tested whether an Apple Watch, a new app, and weekly health coaching could help dementia caregivers improve their sleep and mood. 21 caregivers wore the watch to track their activity and sleep patterns, and received personalized feedback and support for up to 6 weeks. …

This study tested a new website tool called WeCareToFeedDysphagia to see if it helps reduce stress for people caring for a loved one with dementia and trouble swallowing. 80 caregivers took part, with some getting access to the tool and others getting standard support. The goal w…

This study tested whether smart electric vehicles can detect and improve walking problems in people with neurodegenerative diseases like Parkinson's or dementia. 120 participants aged 60-85 with mild to moderate walking issues took part. The goal was to see if these vehicles coul…

This study tested a telehealth program that combines music therapy with social work support for older adults living at home. Twenty people aged 65 and older, some with dementia, took part in video sessions to see if it improved their well-being, thinking skills, and feelings of l…

This study tested a mobile app designed to help people caring for a loved one with dementia. 59 caregivers in Singapore used the app for one month or were placed on a waiting list. The goal was to see if the app could reduce feelings of depression and burden, and improve knowledg…

This study tested whether a training program for home care workers could help improve nutrition for people with dementia living at home. Researchers worked with families and care workers to adapt an existing nutrition program and see if it was practical and acceptable. The goal w…

This study tested whether a nurse-led walking and sit-to-stand program is practical and liked by older adults with cognitive issues like dementia in transitional care. Six participants took part to see if the program could improve strength, mobility, and quality of life. The main…

This study tested whether a special pain scale called PAINAD helps emergency room staff better assess and treat pain in people with dementia. Over 700 older adults with dementia and hip pain took part. The goal was to see if using this tool leads to quicker and more accurate pain…

This study tested a new way to help people with Alzheimer's or dementia and their caregivers talk about and plan for future medical care. 38 people with memory challenges and their care partners took part. The goal was to see if the communication tool could help them feel more pr…

This study tested a method to safely reduce unnecessary medications in people with dementia who take many pills. Researchers compared a patient-priorities approach to usual care in 45 participants, looking at medication changes, treatment burden, and side effects. The goal was to…

This study tested a computer system that helps doctors identify older patients at risk for memory problems or dementia. Over 3,200 adults aged 65 and older took part. The system used health records and risk models to alert doctors, aiming to improve early detection and care plann…

This study tested a new program called 'HBPC Dementia Care Quality at Home' for people with dementia and their caregivers who receive home-based primary care. Researchers worked with 50 participants to see if the program was practical and helpful for both caregivers and clinic st…

This study looked at whether a 90-minute, game-based class could improve how healthcare students think and feel about people with dementia. About 400 students took part in the single session, which included a lecture, a game called N-impro, and short dramas. Researchers measured …

This study tested a training program for home care workers who care for people with dementia. The program used realistic scenarios to help workers improve their empathy, preparedness, and competence. 70 full-time home care workers took part. The goal was to see if this type of tr…

This study looked at whether emergency room pharmacists can help reduce the use of certain risky medications (like sedatives) in people with dementia or mild memory problems. Researchers worked with 300 patients to see if pharmacists could safely recommend stopping these drugs an…

This study looked at over 6,000 Medicare patients with mild cognitive impairment or dementia to see how amyloid PET scans affect their care and health outcomes. Researchers compared results between different racial and ethnic groups to improve precision in diagnosis and treatment…

This study surveyed 219 family caregivers of people with dementia to learn how swallowing difficulties (dysphagia) impact their daily lives and sense of burden. Caregivers completed a one-time online questionnaire about their loved one's swallowing issues, their own stress, and h…

This study tested a simple idea: sending gentle reminders (nudges) to doctors and caregivers to help reduce or stop certain high-risk medications in people with dementia. Researchers worked with 250 patients aged 65 and older to see if this approach was practical and could be mea…

This study tested whether a single virtual reality (VR) session, where caregivers experience what it's like to have dementia, could increase their empathy and improve their attitudes. 227 caregivers of people with dementia took part. The results showed that the VR program helped …

This study tested a program to help nursing home staff talk with Alzheimer's patients and their families about future medical care. The goal was to make sure patients' treatment wishes are known and followed, which could reduce stressful and unwanted hospital visits. Over 47,000 …

This study tested a program to help people with dementia in assisted living document their medical care wishes, like whether to be resuscitated or hospitalized. Over 2,300 residents took part, with some receiving the planning program and others usual care. The goal was to see if …

This study tested a new online program called the Brain Health Support Program (BHSP) that teaches people about dementia and how to lower their risk through healthy habits like diet, exercise, and social connection. Twenty adults with mild memory concerns or a family history of d…

This study followed 404 older adults for 10 years after hip fracture surgery. Researchers checked if early signs of Alzheimer's in the brain (measured from spinal fluid) were linked to how long patients lived. The goal was to understand if pre-existing brain changes affect long-t…

This study followed over 18,000 Taiwanese adults to see if a vegetarian diet is linked to lower rates of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers used health insurance records to trac…

This study checks if a questionnaire called SCREEN can correctly find older adults (55+) who are at risk of malnutrition, especially those with mild memory loss or dementia and those living in retirement homes. Researchers compared SCREEN results with a dietitian's expert assessm…

This study tested a special learning technique to help family caregivers better remember information about Alzheimer's and dementia symptoms and treatments. Sixty-five informal caregivers from the U.S. took part in online exercises that used repeated practice to improve their kno…

This study tested whether a special learning technique called retrieval practice helps dementia caregivers remember important information about symptoms and treatments. 73 caregivers took part in online sessions. The goal was to see if this approach improves long-term knowledge a…

This study tested whether a community health worker (CHW) program is practical and well-liked by people with dementia and their caregivers after leaving the hospital. Researchers enrolled 34 patients and their caregivers to receive telephone support from a CHW coach. The goal was…

This study examined how the COVID-19 pandemic affected primary care for people with chronic conditions like diabetes, heart failure, and depression in Canada. Researchers analyzed health records from nearly 920,000 adults to see changes in doctor visits, tests, and treatments. Th…

This study looked at whether restoring proper chewing function can improve brain health and delay cognitive decline. Researchers worked with 150 adults who needed dental treatment or had misaligned teeth. They used brain scans and thinking tests to see if fixing dental problems h…

This completed study tested whether an AI platform can detect mild cognitive impairment and dementia by analyzing speech. Researchers compared language patterns from 196 older adults (55+) with standard cognitive tests. The goal was to see if speech changes can serve as a screeni…

This study tested a social robot that plays trivia and gives reminders to people with Alzheimer's or other dementias living in assisted care. The goal was to see if the robot helps improve engagement, mood, and quality of life. 26 residents, family members, and staff took part. T…

This study tested a special course called Caregiving While Black-LIVE for Black family members or friends caring for someone with dementia. The course aimed to help caregivers feel more understood by doctors and better able to find and use health information. Forty Black caregive…

This study tested a set of tablet games called VibrantMinds in 26 older adults with mild cognitive impairment or dementia. The games are designed to measure thinking skills like memory and attention in a fun, engaging way. Researchers want to see if these games can work as well a…

This study looked at whether people who develop long-term nerve pain after shingles have a higher chance of getting dementia later in life. Researchers analyzed health records from over 68,000 adults aged 40 and older. They compared those with postherpetic neuralgia to those with…

This study followed 169 elderly patients (over 60) with depression who were treated at specialized clinics in Norway. Researchers checked on them after one and three years to see how their depression changed and whether they developed dementia. The goal was to learn about long-te…

This study looked at whether measuring the skin's electrical activity can give an early warning before a person with dementia becomes agitated or aggressive. 21 patients from a dementia unit took part. The goal was to see if these skin signals could predict outbursts, which might…

This study tested a program called Home Alone for adults aged 55+ with mild memory or thinking problems who live alone. The goal was to see if the program was useful and acceptable. Participants worked with a coach in weekly one-hour sessions over 3 to 6 months, and the study mea…

This study tested a new computer system that uses artificial intelligence to help doctors better diagnose and treat complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected information from 635 people, including healthy volunteers, to see if the …

This study tested whether starting cognitive training early in the hospital and continuing it at home for 12 weeks could improve thinking and memory in older adults (65+) who experienced delirium. A total of 283 participants were randomly assigned to receive the cognitive interve…

This study tested a program called Patient Priorities Care for 178 people with dementia or mild cognitive impairment. Participants received a packet before their doctor visit and could talk with a trained facilitator about their personal care goals. The study aimed to see if this…

This study tested whether a fun, interactive program using music and dance could help parents and children learn more about Alzheimer's disease. Over 2,200 families from New York City schools took part. Researchers measured their knowledge before and after the program, and again …

This study looked at how common mild cognitive impairment is among adults aged 50-65 in Kerala, India, and tested a multi-part program to help prevent further memory loss. Researchers enrolled 481 participants and measured changes in thinking skills like attention, memory, and la…

This study tested whether a virtual reality (VR) program could help older adults with mild cognitive impairment learn more about dementia and improve their health skills. 139 participants aged 65 and older were split into two groups: one used a VR education module, and the other …

This study tested a program where trained senior volunteers help families caring for someone with Alzheimer's or dementia. The goal was to see if these companions could connect families to helpful community services, reduce caregiver stress, and improve the person's well-being. 4…

This study tested two ways to train nursing home and assisted living staff to provide better care for LGBTQ+ residents with Alzheimer's or dementia. Over 700 staff members from Minnesota took part in either an in-person or online training program. The goal was to see if the train…

This study followed 229 adults over age 40 who had a recent stroke to learn what factors might lead to dementia or memory problems later. Researchers looked at medical history, brain scans, and daily living skills. The goal was to identify clues that could help predict or prevent…

This study looked at whether self-compassion — being kind and understanding toward yourself — is linked to a better quality of life for older adults recently diagnosed with dementia. Researchers also wanted to see if feeling less threatened by the diagnosis helps explain that lin…

This study tested whether a computer tool that scans electronic health records can identify older adults (65+) who may have undetected mild cognitive impairment or Alzheimer's disease. Researchers then used patient-friendly messages to encourage these individuals to get a cogniti…

This study tested a new approach to help older Latinos with dementia get better care. Researchers trained primary care doctors in Kansas City to better detect dementia and refer patients to a health navigator. The navigator then provided support and connected families to communit…

This study looked at whether cochlear implants, devices that help people hear, can also improve thinking and memory in adults aged 65 and older with hearing loss. Researchers gave participants memory and attention tests before surgery and again at 6 months, 1 year, and 5 years af…

This study looked at over 11,000 adults in Trøndelag, Norway to find out how many have dementia and whether they have been diagnosed. Researchers used standard tests to measure memory and thinking skills. The goal was to get accurate numbers on dementia rates and see who is missi…

This study tested a program that screens older adults (60+) for memory and thinking problems after a stay in the intensive care unit (ICU). About 109 people took part to see if the screening was practical and helpful. The goal was to find cognitive issues early and connect patien…

This study reviewed medical records of 683 older adults with dementia to see if their antiplatelet medications (like aspirin) were prescribed appropriately according to guidelines. Researchers looked at different types of dementia and compared real-world prescribing to recommende…

This study adapted a program called BECOME to help people with dementia or mild cognitive impairment and their caregivers manage chronic diseases like diabetes and high blood pressure, as well as mental health issues like depression and anxiety. The program was adjusted with inpu…