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Hip fracture Patients' brain markers may predict 10-Year survival

NCT ID NCT07443566

Knowledge-focused Sponsor: Bengt Nellgård Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 404 older adults for 10 years after hip fracture surgery. Researchers checked whether early signs of Alzheimer's in spinal fluid or cognitive tests were linked to how long patients lived. The goal is to understand if hidden Alzheimer's changes affect long-term survival after a hip fracture.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify people with hip fractures who may have undetected early Alzheimer's, allowing for earlier monitoring or care.
What could go wrong
This is an observational follow-up, not a treatment trial. It cannot prove cause and effect, only show possible links. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

404 people

The number who actually took part.

Started

Oct 2013

Finished

Jun 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Older adults (≥65 years) who were admitted for acute hip fracture and underwent surgical repair under spinal anesthesia at Sahlgrenska University Hospital, Mölndal, Sweden. Participants were originally enrolled between October 2013 and June 2015 and had pre-fracture cognitive status assessed using the Clinical Dementia Rating scale and cerebrospinal fluid biomarkers related to Alzheimer's disease collected at baseline. The present study is a long-term follow-up of this cohort.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant enrolled in the original acute hip fracture cohort (index surgery during Oct 2013-Jun 2015 at Sahlgrenska University Hospital, Mölndal) * Available personal identity number enabling linkage to Swedish registries * Baseline cognitive assessment (CDR) and/or CSF biomarker data available from the index admission Exclusion Criteria: Missing linkage information preventing ascertainment of vital status \-

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer's disease Dementia Hip fractures (icd-10 72.01-72.2)

Contacts and locations

Locations

  • Sahlgrenska University Hospit

    Mölndal, Västra Götaland County, 431 80, Sweden

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