Vitamin B3 dose trial hopes to slow Alzheimer's brain decline

NCT ID NCT05617508

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested different doses of nicotinamide riboside (a form of vitamin B3) in 80 people with early Alzheimer's disease. The goal was to find the dose that best boosts brain energy levels and changes brain metabolism with the fewest side effects. Participants took placebo or 1000-3000 mg of NR daily for 12 weeks, undergoing brain scans, spinal taps, and cognitive tests.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haraldsplass Deaconess Hospital

    Bergen, Vestland, 5009, Norway

  • Haukeland University Hospital

    Bergen, Vestland, 5021, Norway

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