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A stumble before memory slips? study tests if falls predict Alzheimer's

NCT ID NCT04949529

Completed Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study looks at whether falls and mobility problems can signal very early, preclinical Alzheimer's disease in older adults who are still cognitively normal. Researchers will follow 355 volunteers aged 65 and older, some with and some without biological signs of Alzheimer's, tracking falls monthly for up to two years. The goal is to understand if changes in balance and walking occur before memory loss begins.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If falls prove to be an early warning sign, this could lead to a simple way to identify people at risk for Alzheimer's disease years before memory problems appear.
What could go wrong
This is an observational study, not a treatment trial. It can only show a link, not cause and effect. The results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE FALL

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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