Lifestyle makeover may stave off dementia in At-Risk seniors

NCT ID NCT06488430

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how common mild cognitive impairment is among adults aged 50-65 in Kerala, India, and tested a one-month program combining nutrition advice, exercise, brain games, social support, and heart health management. The goal was to see if this approach is practical and acceptable for preventing further cognitive decline. 481 participants were enrolled, and those with mild cognitive impairment received the intervention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

multidomain intervention package (nutritional advice, physical activity, cognitive stimulation training, social support, and management of vascular risk factors)

What this could lead to

If the intervention is found feasible, it could lead to larger clinical trials testing whether a combination of lifestyle changes can prevent or slow cognitive decline in older adults.

What could go wrong

This is a small, one-month feasibility study, not a large trial. The results may not apply to other populations, and the short duration cannot show long-term benefits or risks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Believers Church Medical College

    Tiruvalla, Kerala, 689 103, India