New program aims to cut unnecessary pills for dementia patients

NCT ID NCT04938648

Completed Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a program where a pharmacist worked with people living with dementia, their care partners, and their doctors to review and reduce unnecessary medications. The goal was to simplify medication routines and lower treatment burden. The study included 138 participants aged 65 and older with dementia and multiple chronic conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pharmacist-led deprescribing intervention (educational materials, telehealth visit, and provider communication)
What this could lead to: If successful, this approach could help people with dementia take fewer unnecessary medications, reducing side effects and simplifying daily care.
What could go wrong: This is a small feasibility study, not a large trial. The program may not work for everyone, and deprescribing must be done carefully to avoid withdrawal risks.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE AND RELATED DEMENTIAS POLYPHARMACY

Contacts and locations

Locations

Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States
Kaiser Permanente

Aurora, Colorado, 80014, United States

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