DEMENTIA

This study is testing an online program called e-ALIGN. It aims to help older adults with mild memory problems or dementia, and their caregivers, work with doctors to safely stop or reduce medications that might be harmful or unnecessary. The program sends educational videos and …

This study is testing whether combining two treatments—a drug that enhances brain signaling (DAOIB) and omega-3 fatty acids—works better than the drug alone to help people with early Alzheimer's disease or mild memory problems. It will involve 140 participants who will take the t…

This study is testing whether deep brain stimulation can improve memory and thinking skills in people with early Alzheimer's disease. Researchers will implant small electrodes in the brain to deliver mild electrical pulses to areas involved in memory. The study will measure chang…

This study is testing whether providing hospital-level care at home is better than usual hospital care for people with moderate to severe dementia. It will involve 200 participants who have been hospitalized recently and live with or near a family caregiver. The main goal is to s…

This study aims to test a Greek version of a common memory and thinking test called the MoCA. Researchers will give the test to about 250 people, including healthy adults and those with memory problems, to see if it works reliably in Greek. The goal is to provide doctors with a b…

This study is testing a new AI tool called LUMEN that helps family members and caregivers describe their loved one's memory and thinking changes more clearly. About 60 caregivers and doctors will use the tool in memory clinics to see if it makes sharing information easier and mor…

This study aims to prevent serious complications after major heart and vascular surgery in adults 65 and older. Researchers will test whether personalized pre-surgery training (including physical exercise, brain games, and social support) and special monitoring during surgery can…

This large study aims to find out if getting the shingles vaccine can also help prevent major heart problems and dementia in older adults. About 162,000 people in Denmark aged 65 and older will be randomly chosen to either receive the two-dose shingles vaccine or not receive it. …

This study is testing a program called KINDER, designed to prevent psychological abuse and improve the quality of care for people living with dementia. It will work with 260 family caregivers, teaching them skills to manage stress and build better relationships. The goal is to re…

This study is developing and testing a new screening tool to help primary care doctors spot signs of neglect in older adults with dementia. It also involves creating a support program delivered through in-person sessions and a mobile app for caregivers. The research will test how…

This study is testing whether a simple smartphone app is easy and acceptable for older adults and their caregivers to use. The app offers activities like drawing, Tai-Chi, and prayer reading, which may help with emotional stability and social connection. Over six weeks, 40 partic…

This study is testing a self-paced, online program called WeACT, designed to help family members caring for a relative with dementia. The program teaches skills to manage difficult thoughts and feelings, aiming to reduce stress, depression, and anxiety. Researchers want to see if…

This study is testing whether using an AI-powered smart electric vehicle for walking (gait) training is safe and helpful for people with Parkinson's disease or dementia. About 120 participants aged 50-85 will use the vehicle for training sessions 2-3 times per week for 2 to 12 we…

This study is testing if a supervised ketogenic diet (a very low-carb, high-fat eating plan) can help reduce pain and improve thinking in older adults who have both osteoarthritis and mild memory problems. Ten participants will follow the diet, and researchers will check their pa…

This study is testing whether a non-contact sleep monitor can help improve sleep for people with Alzheimer's living in long-term care. For 100 participants, the monitor will track sleep for four weeks. Researchers want to see if sharing this sleep data with care staff leads to be…

This study is testing whether daily light therapy can help reduce agitation and behavioral symptoms in people with dementia. Researchers will enroll 70 hospitalized patients with dementia who experience these symptoms. Participants will receive light therapy for five days to see …

This study is testing whether a painless, low-level laser applied to specific points on the body can help reduce agitation, anxiety, and other distressing symptoms in people with dementia. It will involve 60 participants living in care facilities. Researchers will use the laser t…

This study is testing whether a virtual reality program can help family members caring for loved ones with dementia. It aims to help caregivers find better balance between their own needs and caregiving duties, potentially reducing stress and strain. The program uses VR scenarios…

This study tests whether connecting dementia caregivers with trained peer mentors and personalized community resource lists can improve their well-being. Over 330 caregivers will receive education, resource information, and ongoing text message support for 12 months. Researchers …

This study will test if guided activities in hospital therapeutic gardens, like gentle gardening or nature walks, can help two groups of patients. For elderly inpatients with dementia, researchers want to see if it reduces agitation and restlessness. For patients recovering from …

This study is testing a culturally adapted online program called Tele-Savvy for Latino caregivers of people with Alzheimer's or dementia. The program aims to help caregivers build skills and confidence through weekly group video sessions and instructional videos. Researchers want…

This study is testing whether a one-month music program, delivered through a phone app, can help people with dementia fall asleep faster and sleep better. It will also check if the music reduces stress for the family members who care for them. The researchers will enroll 144 peop…

This study aims to help family and friends who care for seriously ill older veterans living in rural areas. It will test whether connecting these caregivers with a trained community health worker for six months can reduce their stress and improve their satisfaction with care. The…

This study tests whether a simple support program can help reduce stress for people caring for loved ones with dementia. Participants who previously took part in an observational study will receive six weeks of educational text messages or emails about caregiving and stress manag…

This study is testing whether giving home health aides extra training in dementia care helps reduce difficult behaviors in older adults with memory problems and improves their quality of life, as well as the well-being of their family caregivers. It will involve 60 pairs of patie…

This study is testing whether playing interactive games with a social robot can help older adults with mild memory problems or dementia. About 80 participants will either play these robot games twice a week for 12 weeks or receive their usual care. Researchers will use questionna…

This study is testing a new support program for family members who care for a loved one with dementia at home. It pairs families with a specialized nurse and gives them an app for quick expert advice. The goal is to see if this help reduces caregiver stress, improves difficult de…

This study is testing a new 6-month training program for assisted living staff to improve their daily care interactions with residents who have Alzheimer's or related dementias. It will involve 100 residents across four communities. The goal is to see if better interactions can r…

This study is creating and testing a text message program to support family caregivers after their loved one with dementia is discharged from the emergency room. The goal is to see if regular, supportive texts can help caregivers feel more prepared and less burdened during the tr…

This small pilot study is checking if over-the-counter hearing aids are a practical and acceptable option for older adults who have a genetic risk for dementia and mild-to-moderate hearing loss. It will enroll 20 people aged 50+ to see if they can and will use the devices regular…

This study aims to discover the most effective ways for nurses and therapists to talk to people with dementia to help them stand and walk sooner after hip fracture surgery. Researchers will video record up to 50 real-life care sessions on hospital wards to analyze the specific wo…

This study is testing a new digital toolkit that uses artificial intelligence to help assess and monitor symptoms like pain and distress in people with mild to moderate dementia. Researchers will recruit 150 participants across six countries to see if the toolkit is easy to use a…

This study is testing a new way to train home care workers who are new to caring for people with dementia. It compares an 8-week interactive virtual training program against traditional group discussions to see which better improves workers' knowledge, communication skills, and e…

This study aims to test a community education program designed to reduce stigma and improve understanding of dementia in rural Kenya. Researchers will first survey and interview local residents to understand current beliefs, then refine and test a four-session group program. The …

This study is creating a decision aid to help patients with early dementia, their families, and doctors make shared choices about medications. Researchers will test how well the tool reduces uncertainty and improves confidence in decision-making. The study involves 100 participan…

This study aims to find better ways to detect Alzheimer's disease early, especially in its mild stages, within the Hong Kong community. Researchers will follow 2,500 older adults for 2-3 years, using simple blood tests and comparing them to brain scans. The goal is to see if thes…

This study aims to clarify whether eating nuts helps prevent major chronic diseases like diabetes, heart disease, cancer, and dementia. It will combine and analyze health data from over one million adults across the globe who have been tracked for at least five years. The goal is…

This study is testing whether a simple walking monitor can help track early signs of memory problems in older adults. Researchers will have 150 participants wear special insoles and ankle devices to measure their walking patterns both in a lab and at home for one week. The goal i…

This pilot study is testing a new digital tool, called the Dementia Journey Companion, designed to help people with mild to moderate dementia plan for their future care. The tool uses artificial intelligence to guide conversations and help patients document their goals, wishes, a…