DEMENTIA

This study tests whether providing acute hospital care at home, instead of in a hospital, improves outcomes for people with moderate to severe dementia. Two hundred participants will be randomly assigned to either home-based acute care or usual hospital care. The main goal is to …

This study tests whether giving home health aides extra training on dementia care can help reduce troubling behaviors in older adults with dementia or mild cognitive impairment. It also looks at whether this training improves quality of life for both the patients and their care p…

This study tests a program called KINDER, designed to help family caregivers of people with dementia reduce psychological elder abuse and improve the quality of care. About 260 caregivers will be randomly assigned to receive the KINDER training or usual care. The program focuses …

This study tests whether playing interactive games with a social robot can improve thinking skills, mood, and quality of life in older adults with mild cognitive impairment or dementia. About 200 participants aged 50 and older will be split into two groups: one will play robot ga…

This study tests whether a drug that boosts NMDA receptors, combined with omega-3 fatty acids, can improve memory and daily function in people with early Alzheimer's or mild cognitive impairment. About 140 participants will take either the combination or a placebo for 24 weeks. R…

This study will test if a painless laser pen, used on specific body points (acupoints), can improve behavioral and psychological symptoms like agitation or mood changes in people with dementia. About 60 participants will be enrolled. The goal is to see if this non-drug approach c…

This study looks at whether a trained peer mentor, along with text messages over 12 months, can help caregivers of people with dementia feel less lonely and more confident finding end-of-life resources. About 330 caregivers will take part. The goal is to improve caregiver well-be…

This study tests a virtual reality program designed to help family caregivers of people with dementia find a better balance in their lives. Researchers will enroll 60 caregivers to see if the VR experience reduces role strain and improves quality of life. The goal is to ease the …

This study tests a self-paced web program called WeACT for adult family caregivers of relatives with dementia. The program teaches skills to handle difficult thoughts and feelings. Researchers want to see if it is practical and helpful for improving mental health and coping. Part…

This pilot study at Mayo Clinic tests whether daily light therapy can reduce behavioral and psychological symptoms like agitation in people with dementia. Researchers will enroll 70 inpatients and measure how well they tolerate and complete the 5-day light sessions. The goal is t…

This study looks at whether a carefully planned ketogenic diet can reduce pain and improve thinking in people who have both osteoarthritis and mild cognitive impairment. Ten adults will follow the diet under supervision, and researchers will check their pain, physical function, a…

This study tests whether trained community health workers can reduce stress and improve satisfaction for people caring for seriously ill older veterans in rural areas. About 480 care partners will be randomly assigned to receive extra support or usual care. The goal is to lighten…

This study tests a program where specially trained nurses and a smartphone app support family caregivers of people with dementia. The goal is to help keep the person with dementia living at home longer, reduce caregiver stress, and manage difficult symptoms. About 554 families wi…

This study tests whether training with an AI-powered smart electric vehicle can safely improve walking and reduce falls in people with Parkinson's disease or dementia. About 120 participants aged 50-85 who can walk but have unsteady gait will use the vehicle for gait training. Th…

This study will test whether guided nature-based therapy, such as forest bathing and gardening in hospital gardens, can improve the wellbeing of elderly patients with dementia and patients recovering from stroke or brain injury. Researchers plan to enroll 1,600 participants at Ch…

This study tests whether a smartphone app called utmbHealthyBrain is easy for older adults and their caregivers to use. The app includes drawing, Tai-Chi, meditation, and a sharing feature to connect with family. Over six weeks, 40 participants will try the app at home. The goal …

This study tests a program to improve how staff and residents with dementia interact during daily care. Researchers will work with 100 residents aged 55+ in assisted living to see if the program reduces distress and improves engagement. The goal is to make care more positive and …

This study tests whether a low-intensity program of educational texts and emails can reduce stress and burden for people caring for a loved one with dementia. Twenty caregivers who previously joined an observational study will receive automated supportive messages for six weeks. …

This study will enroll 1,200 older adults (65+) who are at higher risk for complications after heart or blood vessel surgery. Researchers will test a computer program that predicts risks and also study whether personalized pre-surgery coaching and special care during surgery can …

This study is creating a decision aid to help people with early dementia, their caregivers, and doctors talk through medication options together. Researchers will test if the tool reduces uncertainty and improves shared decision-making. About 100 patients, caregivers, and clinici…

This study tests whether a computer-based virtual trainer can improve how new home care workers communicate with people who have dementia. About 102 workers with less than one year of experience will take part. The goal is to see if the training boosts their knowledge, communicat…

This study will test a new digital toolkit that uses artificial intelligence to assess pain and distress in 150 people with mild to moderate dementia. Participants will use wearable sensors and diary recordings to help researchers see if the toolkit is easy to use and accurate. T…

This study will test a special monitor that tracks sleep without touching the person. It is for 100 people with Alzheimer's or related dementias living in long-term care facilities. For the first two weeks, sleep data is collected but not shared. For the next two weeks, staff and…

This study is testing a new digital tool called the Dementia Journey Companion (DJC) that helps people with mild to moderate dementia plan their future care. About 150 participants will use the tool to share their preferences for daily living, medical treatment, and end-of-life c…

This study aims to validate an Italian version of the dynamic Neurocognitive Adaptation (dNA) Scale, a questionnaire that measures how much older adults engage in physical, mental, creative, and social activities. Researchers will recruit 265 people aged 65 and older, including t…

This study tests a program designed to help primary care doctors identify dementia in patients who have memory concerns but haven't been diagnosed yet. Researchers will compare this program to usual care in 80 adults over 6 months. The goal is to see if the program leads to more …

This study tests a program designed to reduce stigma and improve understanding of dementia in rural Kenya. Researchers will first survey 600 people and interview 20 to understand local beliefs. Then, 184 adults from Mbooni Sub county will take part in a community program to see i…

This study is developing and testing a text-message program to support caregivers of people with dementia after an emergency room visit. About 80 caregivers will receive text messages for 30 days to see if the program is easy to use and helpful. The goal is to improve the transit…

This study looks at whether Alzheimer's disease markers in blood differ among ethnic groups in central Barcelona. Researchers will also examine how age, income, education, and health conditions affect these markers. The goal is to identify barriers to using these blood tests in p…

This study is creating a screening tool for primary care doctors to identify signs of neglect in older adults with dementia. It also tests a support program delivered in person and through an Android app. About 40 caregivers will try the system and give feedback on how easy and h…

This study tests a wearable system that tracks walking patterns to detect early signs of Alzheimer's or related dementias. Researchers will collect gait data from 150 older adults (55+) who are healthy, have mild cognitive impairment, or have dementia. Participants either walk in…

This study looks at whether over-the-counter hearing aids are a practical option for older adults with hearing loss who are also at higher risk for dementia. Twenty people aged 50 and older with mild to moderate hearing loss and a specific genetic risk factor will try the devices…

This study looks at how doctors and nurses talk to people with dementia after hip fracture surgery. The goal is to find which words and phrases work best to encourage them to stand or walk early. Researchers will video record real conversations on hospital wards and analyze them …

This study will follow 2,500 elderly people in Hong Kong for 2-3 years to find better ways to detect Alzheimer's disease early. Researchers will use blood tests and brain scans to track changes in memory and thinking. The goal is to create a Chinese-specific resource to improve e…

This study checks how well a Greek version of the Montreal Cognitive Assessment (MoCA) works for spotting early signs of memory loss and dementia. Researchers will test 250 Greek-speaking adults aged 55 to 85 to see if the test is reliable and accurate. The goal is to give doctor…