Can a simple quiz predict brain health in aging? italian study aims to find out
NCT ID NCT07533084
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test an Italian version of a questionnaire called the dynamic Neurocognitive Adaptation (dNA) scale in 265 older adults, including those with normal aging, mild memory complaints, or dementia. The goal is to see if higher scores on the scale—reflecting more engagement in physical, cognitive, creative, and social activities—are linked to better memory and brain function. Participants will complete interviews, memory tests, and questionnaires, and some will have their existing MRI scans analyzed. This is a validation study, not a treatment, so it aims to improve understanding rather than offer a direct benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a simple tool to assess how physical, cognitive, and social activities relate to brain health in aging.
- What could go wrong
- This is an early validation study, not a treatment trial. It only measures correlations, not cause and effect, and results may not apply outside Italy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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IRCCS Campus Bio-Medico
Roma, RM, 00128, Italy
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IRCCS Centro San Giovanni di Dio Fatebenefratelli
Brescia, BS, 25125, Italy
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IRCCS Fondazione Mondino
Pavia, PV, 27100, Italy
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IRCCS Istituto Neurologico Carlo Besta
Milan, Michigan, 20133, Italy
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IRCCS Neuromed - Istituto Neurologico Mediterraneo
Pozzilli, IS, 86077, Italy
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IRCCS Ospedale San Camillo
Venezia, VE, 30126, Italy
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IRCCS Ospedale San Raffaele
Milan, Michigan, 20132, Italy
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IRCCS San Martino
Genova, GE, 16132, Italy
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