Menstrual disorder

This study tested a handmade frameless IUD that releases the hormone levonorgestrel in 15 women at high risk of IUD expulsion due to conditions like adenomyosis or heavy bleeding. The device was made by combining an anchor system with a standard IUD after removing its T-shaped ar…

This early study tested whether a naturally occurring hormone called kisspeptin can stimulate reproductive hormones and help women with hypothalamic amenorrhea (a condition where periods stop due to low hormone levels) release eggs. Thirteen women received pulsatile injections of…

This study tested two non-drug approaches—FEMOB mobilization and MOPEXE exercises—for reducing pain in women with primary dysmenorrhea (period pain). 72 women aged 18-30 were split into four groups: one received FEMOB, one MOPEXE, one electrotherapy only, and one no treatment. Th…

This study investigates whether an extract from snakehead fish (Ophiocephalus striatus) can reduce menstrual pain in teenage girls with primary dysmenorrhea—cramps without an underlying disease. The trial gives participants either the fish extract or a placebo for 14 days before …

This study tests whether eating specific seeds at different times of the month can help women ages 18-45 with irregular periods, cramps, and PMS. Participants will eat flax and pumpkin seeds during the first half of their cycle, then switch to sunflower and sesame seeds during th…

This trial investigates whether daily seed cycling capsules can reduce common PMS symptoms like cramps, bloating, fatigue, and mood swings. Forty women aged 18 to 45 with a history of menstrual symptoms will take the capsules for two menstrual cycles and report changes through qu…

This study tested whether a food supplement can reduce the discomfort of premenstrual syndrome (PMS) in 110 healthy women aged 18 to 45 with mild to moderate symptoms. Half took the supplement and half took a placebo for three menstrual cycles. Researchers tracked symptom severit…

This study tests whether a podcast-based education program can reduce the severity of premenstrual syndrome (PMS) symptoms and improve quality of life in female university students. Participants listen to eight podcast episodes over four weeks that cover topics like understanding…

This study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …

This study tested whether auricular acupressure (pressing points on the ear) can reduce symptoms of premenstrual syndrome (PMS) in female college students. 66 participants received either real or sham acupressure over 8 weeks. Researchers measured changes in PMS symptoms and qual…

This study tested whether combining motor imagery (mentally practicing movements) with gentle exercise can reduce menstrual pain and improve coordination. Forty-eight women with moderate to severe period pain were split into three groups: one did motor imagery plus exercise, one …

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This study looked at whether acupuncture can reduce pain and improve daily life for women with painful periods (primary dysmenorrhea). 64 women aged 18-35 with regular cycles and moderate to severe pain took part. Researchers measured pain levels and quality of life before and af…

This study tested whether spinal stabilization exercises could help women with painful periods. Fifty women aged 18-30 with regular cycles and no childbirth history were split into two groups: one did the exercises, the other did not. Researchers measured pain, symptoms, and dail…

This study looked at whether lifestyle changes can help reduce period pain in obese women aged 18 to 25. 67 women with moderate to severe pain took part. Researchers measured pain levels, severity, and other factors before and after the program.

This study tested whether regular footbaths during the luteal phase (the week or two before a period) could help women with premenstrual syndrome (PMS). 92 women participated, with one group receiving footbath therapy and the other receiving no treatment. Researchers measured sym…

This study looked at whether kinesio taping (a special elastic tape placed on the skin) can quickly ease period pain and related symptoms like trouble sleeping and fear of moving. Researchers compared real taping to a fake (sham) taping in 24 women aged 18-24 with primary dysmeno…

This study tested a four-week online program that teaches women about the science of pain and how to manage it, specifically for period pain. 82 women with moderate to severe menstrual cramps took part, comparing the program plus lifestyle tips to lifestyle tips alone. The goal w…

This study looked at whether teaching college women about nutrition could reduce the severity of premenstrual syndrome (PMS). 210 female students aged 18-30 with mild to severe PMS took part. Researchers measured changes in PMS symptoms, stress levels, and physical activity after…

This study looked at whether spinal manipulation combined with connective tissue massage can reduce pain, menstrual symptoms, depression, and sleep problems in women with primary dysmenorrhea (painful periods). Seventy-five women were split into three groups: one received both tr…

This study compared progressive relaxation exercises (tensing and relaxing muscles while breathing) with isometric exercises (holding muscle contractions) for managing period pain. Sixty women with moderate to severe primary dysmenorrhea took part. Researchers measured pain, othe…

This pilot study tested a portable TENS device for reducing menstrual pain in 34 women with primary dysmenorrhea. Participants used the device on their lower abdomen during pain episodes for up to three cycles. The goal was to see if this drug-free approach could ease pain and im…

This study tested whether teaching women in menopause about good sleep habits (sleep hygiene) could improve their sleep quality and reduce common menopause symptoms like hot flashes and mood changes. Seventy women who had not had a period for at least a year took part. They recei…

This study tested two non-drug approaches for severe period pain: placing a dried Rose of Jericho plant in water near the person, and practicing 4-7-8 breathing exercises. 100 women aged 18-35 with very painful periods took part over three cycles. Researchers measured changes in …

This study looked at whether SuJok therapy—a technique that applies pressure to specific points on the hands and feet—can reduce period pain and improve quality of life in young women with primary dysmenorrhea (painful periods without an underlying medical cause). Researchers enr…

This study looked at whether taking vitamin E together with the painkiller mefenamic acid works better than the painkiller alone for period cramps. Sixty women aged 15-35 with painful periods took either the combination or just the painkiller. Researchers measured pain levels to …

This study looked at whether doing barre and gym ball exercises could reduce pain and distress and improve quality of life in women with painful periods (primary dysmenorrhea). 42 women with moderate to severe period pain took part. They did 30-minute exercise sessions three time…

This study tested whether aerobic exercise or Aviva exercises better relieve menstrual cramps and improve sleep, daily activities, and quality of life. It involved 42 unmarried women aged 20-40 with moderate to severe period pain. Participants were split into two groups, each doi…

This completed study compared an 8-week online yoga program to a conventional exercise routine in 52 women with endometriosis. The goal was to see if yoga could better reduce pain and improve quality of life. Participants practiced meditation, breathing, and gentle poses, while t…

This study tested whether Pilates or aerobic exercises better reduce period pain in young women with primary dysmenorrhea. Thirty-two women aged 18-25 with regular cycles and normal weight did either Pilates or aerobic exercises for 8 weeks. Pain severity and quality of life were…

This study looked at whether laughter yoga can improve quality of life and reduce symptoms of premenstrual syndrome (PMS) in young people aged 18 to 25. Seventy-five participants with regular periods took part. The approach combines breathing exercises, clapping, and playful game…

This study tested whether an 8-session online mindfulness program could reduce PMS symptoms, fear of childbirth, and improve psychological well-being in 126 women with PMS. Participants were randomly assigned to either the mindfulness group or a control group. The results will sh…

This study tested whether doing Pilates online with a live instructor could help women with painful periods. Thirty-four women with primary dysmenorrhea took part in 16 supervised sessions over eight weeks. Researchers measured pain, other symptoms, and trunk muscle endurance to …

This study tested whether laughter yoga can help with premenstrual syndrome (PMS) symptoms and quality of life in young women. Sixty-nine women aged 18-25 with PMS took part in laughter yoga sessions twice a week for four weeks, plus daily practice at home. The goal was to see if…

This study tested two non-drug treatments—post-isometric relaxation and simple stretching—to see which works better for period pain in young women. Forty-four unmarried women aged 18-30 with painful periods did one of the two exercises three times a week for eight weeks. The goal…

This study tested whether an online mindfulness-based healthy living training program could reduce premenstrual syndrome (PMS) symptoms and improve quality of life. 114 women with regular periods and high PMS scores participated. The training involved 8 online sessions over 4 wee…

This study tested the Cycle Syncing Method, which uses an app to guide diet, exercise, and daily activities based on your menstrual cycle phase. Sixty women aged 22 to 42 with regular cycles but bothersome symptoms participated fully online for 12 weeks. The goal was to see if th…

This study tested a daily dietary supplement (DITTO Cycle Supplement) in 40 women aged 18-45 who regularly experience period symptoms like cramps, bloating, fatigue, and mood swings. Over three menstrual cycles, researchers tracked changes in symptom severity and quality of life …

This study looked at whether Kinesio Taping (a special tape applied to the skin) can help reduce menstrual pain in female soccer players aged 15-17 with primary dysmenorrhea (period cramps). 50 teens from a soccer project took part, and researchers compared the real tape to a pla…

This study looked at whether Pilates exercises can reduce pain and other symptoms of dysmenorrhea (period pain). Fifty-six women with menstrual pain were assigned to either mat Pilates, reformer Pilates, or a control group. Researchers measured changes in pain, fatigue, sleep qua…

This study looked at whether music therapy could help college students with premenstrual syndrome (PMS). Twenty participants were split into three groups: one listened to calming music, one sang, and one played instruments. Researchers measured their brain waves, heart rate, musc…

This study looked at whether trigger point massage and stretching exercises can help young women with primary dysmenorrhea (painful periods). Forty-four women aged 18-30 were randomly assigned to exercise, exercise plus massage, or a control group. Researchers measured pain inten…

This study tested a new medicine called KYG0395 to see if it safely reduces pain from menstrual cramps (primary dysmenorrhea). About 280 women aged 18–35 with moderate to severe period pain took either the drug or a placebo over several cycles. Researchers measured pain levels us…

This study tested whether web-based lifestyle training and progressive relaxation exercises could reduce symptoms of premenstrual syndrome (PMS) in women aged 18-35. Sixty-six women were split into three groups: one received lifestyle training, one received relaxation training, a…

This study tested whether adding relaxation exercises (like deep breathing) to stretching can reduce pain and improve quality of life in women with primary dysmenorrhea (painful periods). Twenty sedentary women aged 18-25 participated. The experimental group did both stretching a…

This early-stage trial tested a vaginal gel containing diclofenac, a common pain reliever, in 42 women with painful periods. The gel is designed to deliver the drug locally, potentially reducing side effects. The study focused on safety and how much drug enters the blood and vagi…

This study looked at whether Emotional Freedom Technique (EFT), a simple tapping therapy, can help nursing students with premenstrual syndrome (PMS). 70 female students with PMS were split into two groups: one received 8 weekly EFT sessions, the other no treatment. Researchers me…

This study tested whether Chuna manual therapy (a type of spinal manipulation) can reduce period pain in women with primary dysmenorrhea. Thirty women were randomly assigned to receive either Chuna therapy or physical therapy over several weeks. The main goal was to see if Chuna …

This study looked at people with low or no GnRH, a hormone that controls puberty and fertility. Researchers studied 111 adults and teens to understand how GnRH problems affect the body. The goal was to find new hormone patterns and genetic causes, not to test a treatment.

This study used advanced brain imaging (MRI and MEG) to look for differences in brain structure, chemistry, and activity between people with schizophrenia and healthy volunteers. Over 3,200 adults took part. The goal was to better understand the brain changes linked to schizophre…

This study looked at how diet and exercise changes affect hormones and menstrual cycles in healthy women aged 18-28. Participants followed special diets and exercise programs while researchers measured hormone levels. The goal was to better understand a condition called functiona…

This study looked at 384 women having their first C-section to compare two methods of closing the uterus: one layer of stitches vs. two layers. The goal was to see which method leads to better scar healing and fewer problems like pain or irregular bleeding. Researchers used ultra…

This study looked at how hormonal birth control might help manage inflammatory bowel disease (IBD) symptoms that get worse during a woman's period. Researchers surveyed 50 women with IBD to understand their preferences for birth control and whether they would join a future trial.…

This completed study from the National Institute of Mental Health looked at over 1,500 women to better understand the symptoms of premenstrual syndrome (PMS) and a severe form called PMDD. Researchers used interviews, rating scales, and hormone tests to track mood and behavior ch…

This study looked at whether monthly nutrition education workshops could improve eating habits and reduce premenstrual syndrome symptoms in 50 adolescent female soccer players aged 15-17. Over five months, the workshops covered sports nutrition topics. Researchers measured change…

This study looked at 70 women with severe menstrual pain to understand why some don't get relief from NSAIDs like naproxen. Researchers measured pain changes after taking the drug or a placebo and tested how the brain processes pain. The goal is to find out if central sensitizati…

This completed study surveyed 1,200 women aged 18-55 to explore how different generations manage menstrual symptoms like cramps, pain, and related discomfort. Participants completed questionnaires about their symptoms, attitudes toward menstruation, sleep quality, physical activi…

This study looked at 164 teenage girls with painful periods to understand how their brains process pain. Participants had pain tests and brain scans at the start and again after a year. The goal was to find patterns that might predict who will develop long-term chronic pain. No t…

This study looked at 183 women with menstrual pain to understand why it happens and how naproxen (a common painkiller) relieves it. Using MRI scans, researchers measured uterine activity, blood flow, and oxygen levels before and after taking naproxen or a placebo. The goal is to …

This completed study looked back at the medical records of 74 adolescent girls aged 12 to 21 who had bone density scans. Researchers wanted to find out which girls are most at risk for low bone density (osteopenia or osteoporosis), especially those with missed periods or other gy…

This study looked at 100 women with primary dysmenorrhea (painful periods) to find out what amount of pain reduction is truly meaningful to them. Participants did an 8-week exercise program, and researchers measured pain and other symptoms using standard questionnaires. The goal …