Menstrual disorder

This study looks at whether dulaglutide, a drug used for type 2 diabetes, can help regulate menstrual cycles in adolescent girls with type 1 diabetes who have poor blood sugar control. Researchers will give some participants dulaglutide plus insulin, while others get only insulin…

This study is testing a new robotic system, the Medtronic Hugo™, for performing hysterectomies. It includes 70 patients with conditions like uterine fibroids, endometriosis, or certain cancers. The goal is to see if the robot is safe and can complete the surgery without switching…

This study planned to test whether an etonogestrel implant (Nexplanon) could reduce the need for hysterectomy in women who still had abnormal bleeding or pelvic pain after endometrial ablation. The trial was withdrawn before enrolling any participants, so no data were collected. …

This study tests whether a specific hand massage technique, called Su-Jok seed therapy, can reduce pain and other symptoms like nausea in people with primary dysmenorrhea (painful periods). Researchers will apply the massage to 60 female students and measure pain levels before an…

This study looked at whether eating flax and pumpkin seeds in the first half of the menstrual cycle, and sesame and sunflower seeds in the second half, can reduce premenstrual syndrome (PMS) symptoms. 48 healthy women aged 18-35 with regular cycles took part. The goal was to see …

This study tests whether taking a daily probiotic supplement can reduce menstrual pain and premenstrual symptoms in women. 150 women with moderate-to-severe period pain will take either a high or low dose of probiotics or a placebo for four menstrual cycles. Researchers will trac…

This study looks at whether combining two relaxation techniques—Benson relaxation and Jacobson progressive muscle relaxation—can reduce symptoms of premenstrual syndrome (PMS) in women aged 18 to 30. Fifty-six female students with PMS will be split into three groups: one using Be…

This study looks at whether adding pelvic floor muscle exercises to deep breathing can help reduce pain during periods in women with primary dysmenorrhea. Forty women will be split into two groups: one doing both exercises, the other only deep breathing. Researchers will measure …

This study is testing whether a virtual group therapy called Acceptance and Commitment Therapy (ACT) can help people with severe premenstrual mood symptoms like PMDD or premenstrual exacerbation of mood disorders. Researchers will enroll 50 participants to see if the program is f…

This study looks at whether teenagers and young adults with Polycystic Ovary Syndrome (PCOS) have more fat in their liver than those without PCOS. Researchers will use advanced imaging and tests to measure liver fat, insulin resistance, and cholesterol problems in 80 participants…

This study follows 810 young women aged 18-45 with early-stage breast cancer to understand how treatment affects their menstrual cycles and quality of life. Participants complete questionnaires every six months for up to 42 months. The goal is to identify factors that lead to ear…

This study looks at young women with hypothalamic amenorrhea (missed periods for months or years) to see if their condition is linked to early signs of heart disease. Researchers will use Fitbit trackers and questionnaires to measure stress, activity, and diet, along with blood t…

This study looks at whether estrogen patches can improve mental flexibility and reward processing in young women (ages 14-35) with eating disorders linked to low estrogen. About 120 participants will receive either estrogen patches or placebo for 12 weeks. The goal is to understa…

This study tests three ways to teach teen girls about managing period pain and hygiene: an AI-powered mobile app, face-to-face classes, and a brochure. About 120 girls aged 14-17 will take part, and researchers will check their knowledge and habits after 4 and 8 weeks. The goal i…

This study tests a 10-week online education program for women with functional hypothalamic amenorrhea (FHA), a condition where periods stop due to stress, low energy, or excessive exercise. The program provides self-guided lessons on stress, nutrition, and exercise. Researchers w…

This study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…

This study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …

This study was designed to see how a hormone called GnRH is processed by the body when given through a small pump (OmniPod) instead of a needle. It was meant for healthy women aged 18 to 40 with regular periods. However, the trial was withdrawn before any participants were enroll…