Could talk therapy ease severe PMS? new study tests virtual ACT group

NCT ID NCT06462391

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a virtual group therapy called Acceptance and Commitment Therapy (ACT) can help people with severe premenstrual mood symptoms like PMDD or premenstrual exacerbation of mood disorders. Researchers will enroll 50 participants to see if the program is feasible and acceptable. If it works, it could offer a new treatment option for those who struggle with these symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acceptance and Commitment Therapy (ACT) group therapy

What this could lead to

If successful, this could provide a new, accessible therapy option to help people with severe premenstrual mood symptoms better manage their condition.

What could go wrong

This is a small, early feasibility study with only 50 participants, so it cannot prove effectiveness. The therapy may not work for everyone, and results may not apply to broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

premenstrual dysphoric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Women's College Hospital

    Toronto, Ontario, L5M6N8, Canada

  • Women's College Hospital

    Toronto, Ontario, M5S 1B2, Canada