New gel could ease menstrual cramps without pills
NCT ID NCT05752526
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early-stage trial tested a vaginal gel containing diclofenac, a common pain reliever, in 42 women with painful periods. The gel is designed to deliver the drug locally, potentially reducing side effects. The study focused on safety and how much drug enters the blood and vaginal fluids, not yet on how well it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- diclofenac vaginal gel
- What this could lead to
- If it works, this could offer a new, localized option for managing period pain with potentially fewer side effects than oral painkillers.
- What could go wrong
- This is a very early phase 1 trial with only 42 participants, focused on safety and drug levels, not on proving the gel actually relieves pain. The results may not lead to an effective treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
PARC Clinical Research
Adelaide, Western Australia, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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