PERIODONTITIS

This study is testing a new treatment for severe gum disease that has caused bone loss around teeth. Researchers are comparing a standard cow bone graft to the same graft mixed with an injectable gel made from the patient's own blood (i-PRF). They want to see if the blood gel hel…

This study is testing whether applying a gel containing lovastatin (a type of statin drug) under the gums can improve the results of standard deep cleaning treatment for periodontal disease. It involves 44 adults with gum disease, including both smokers and non-smokers. Researche…

This study is testing two different non-surgical cleaning methods for treating peri-implantitis, a gum infection that can damage the bone supporting dental implants. Researchers will compare a newer, more delicate cleaning technique (MINST) against the standard cleaning method (N…

This small study is testing a new toothpaste designed to help control gum disease (periodontitis). It aims to see if the toothpaste, which contains a new ingredient meant to support healthy mouth bacteria, is effective when used twice daily for three months. The study involves 28…

This study compares two different methods for cleaning teeth to treat gum disease. Patients with moderate to severe gum disease will receive either ultrasonic cleaning or traditional manual cleaning. Researchers will track gum health and bone changes over 12 months to see which m…

This study is testing whether adding low-level laser therapy or a hyaluronic acid gel improves the results of standard deep cleaning for gum disease. Researchers will compare three groups: one receiving only the standard cleaning, one receiving cleaning plus laser, and one receiv…

This study is testing whether a special probiotic-based toothpaste and mouthwash can help improve gum health and blood sugar control in people who have both type 2 diabetes and gum disease. Forty adult participants will receive standard gum cleaning and then use either the probio…

This study is testing whether adding anti-inflammatory diet education to standard gum cleaning treatment helps people with gum disease (periodontitis) get better results. It will involve 100 volunteers who eat a pro-inflammatory diet. Researchers will measure gum health and infla…

This study is testing different biological materials to see which works best for helping bone regrow around teeth during gum surgery. It involves 30 adults with advanced gum disease who have a specific type of bone defect. During a minor surgical procedure, one of four material c…

This study is testing if rinsing with Manuka honey can help control gum disease (periodontitis) in people receiving kidney dialysis. Gum disease is very common and serious in this group. Researchers want to see if adding this natural antibacterial rinse to standard dental cleanin…

This study is testing a modified, less invasive gum surgery technique combined with tissue grafting materials to treat advanced gum disease (periodontitis). It aims to see if this approach can better reduce deep gum pockets, rebuild lost bone support, and improve gum appearance a…

This study aims to see how well standard, non-surgical gum disease treatment works. Researchers will observe 50 patients with moderate to severe gum disease, tracking changes in their gum pocket depth over six months. The study only uses data from routine dental check-ups and tre…

This small pilot study is testing if adding a special gel to standard deep cleaning for gum disease helps the gums heal better. The gel contains hyaluronic acid and an antiseptic. Researchers will measure healing signs, bacteria levels, and patient comfort in about 26 people over…

This study is comparing three different surgical techniques for treating advanced gum disease (periodontitis). It will involve 60 patients with deep gum pockets and bone loss. The goal is to see which surgical approach is most effective at reducing pocket depth, improving gum att…

This study is testing if a liquid made from a patient's own blood can help gums heal better after a deep cleaning for moderate to severe gum disease. In this split-mouth trial, one side of a patient's mouth gets the blood product while the other side gets a standard saline rinse …

This study is testing a new, high-frequency ultrasound tool to see if it can better detect early gum inflammation (gingivitis). Researchers will compare ultrasound images of the gums from 40 healthy volunteers and people with gingivitis. The goal is to see if this tool can spot s…

This study aims to see if digital tools like 3D mouth scanners and special X-rays can find dental problems as well as or better than a standard dentist's exam. Researchers will compare the two methods in 350 adults visiting dental offices for a check-up. The goal is to understand…

This study is testing if a special light therapy, used during dental cleaning, works better than standard cleaning alone to reduce bad breath in people who have both type 2 diabetes and serious gum disease. Researchers will compare the two treatments over six months to see which …

This study is testing a specific injection technique for numbing the gums during surgery for gum disease. It aims to see if this method is as effective as the standard injection at blocking pain. Researchers will measure pain levels during and after the procedure in 60 adult pati…

This study is testing whether adding tongue scraping to standard oral hygiene instructions helps reduce bad breath in people with gum disease. Researchers will compare the standard gum cleaning treatment with and without the use of a tongue scraper. The goal is to see if this sim…

This study is checking if taking ibuprofen (a common anti-inflammatory painkiller) can reduce inflammation and pain after a deep dental cleaning for gum disease. Researchers will measure inflammation markers in the blood and track pain levels in 30 adults with periodontitis. One …

This study aims to understand the short-term effects of different gum disease cleaning methods on the body. Researchers will compare five treatment approaches in 75 adults with moderate to severe gum disease. They will measure bacteria and inflammation markers in the blood before…

This study aims to better understand the body's immune and inflammatory response that causes bone and tissue damage in serious gum disease (periodontitis) and infections around dental implants (peri-implantitis). Researchers will collect saliva, gum fluid, and tissue samples from…

This study aims to understand if bacteria living in the mouth can travel to the arteries in the neck and make fatty plaques there more likely to rupture, which can cause a stroke. Researchers will collect samples from 200 adults already scheduled for artery-clearing surgery to co…

This study aims to understand if there is a link between how well you sleep and the severity of gum disease (periodontitis). Researchers will examine 48 healthy adults, some with gum disease and some without. They will check participants' gum health, ask about sleep and fatigue u…

This study is creating and testing a Hindi-language questionnaire designed to measure how chronic gum disease (periodontitis) affects a person's quality of life. Researchers will give the questionnaire to 180 adult patients with confirmed gum disease to see if it is a reliable an…

This study is testing a Hindi-language questionnaire designed to measure how much gum disease affects a person's daily life and quality of life. Researchers will give the questionnaire to 106 adults in India with periodontitis before and after their standard gum treatment. The go…

This study aims to find simple markers in blood and saliva that can predict how well people with gum disease will heal after standard cleaning treatment. Researchers will observe 180 adults with healthy gums, gingivitis, or serious periodontitis, taking samples before and after t…

This study aims to understand how gum tissue heals differently in people with severe gum disease, particularly comparing smokers and non-smokers. Researchers will collect small tissue samples during routine gum surgery from 46 participants to analyze healing properties and bacter…

This study aims to understand the link between gum disease, smoking, and specific inflammation markers in saliva. Researchers will compare saliva samples from 116 people with and without gum disease, who are either smokers or non-smokers. The goal is to see if these markers could…

This study aims to understand if a specific bacteria called Treponema parvum is linked to gum disease (periodontitis). Researchers will compare plaque samples from 112 people with and without gum disease to see how common this bacteria is. The goal is to gather knowledge about wh…

This study aims to discover new biological markers that can predict which cases of early gum inflammation (gingivitis) will progress to serious, destructive gum disease (periodontitis). Researchers will analyze saliva, gum tissue, and mouth bacteria from 228 adults with early-sta…