Can your own blood heal your gums? new study explores a natural boost for gum disease treatment
NCT ID NCT07293962
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a gel made from a patient's own blood can improve gum healing after standard deep cleaning for moderate to severe gum disease. About 14 adults with gum pockets of 5mm or deeper will receive the blood gel on one side of the mouth and a saltwater rinse on the other. Researchers will measure pocket depth, gum attachment, and bleeding over 3 months to see if the blood product helps.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 14 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2024
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have at least 20 teeth, * American Society of Anesthesiology class I or II * Periodontitis stages II-IV * Bilateral sites of deep periodontal pockets ≥5 mm Exclusion Criteria: * Limited mouth opening or symptomatic temporomandibular joint disorder * Inability to tolerate extended long periodontal treatment and/or hyperactive gag reflex * Current or former smoker or vape user * Pregnant and/or breastfeeding * Having diabetes mellitus type I or II * Having bleeding disorder or is on anticoagulants * Underwent periodontal treatment and/or surgery in past 6 months prior * Undergoing orthodontic therapy, or completed in past 3 months prior * On or had anti-inflammatory drug(s) in past 3 months prior * On or had antibiotic(s) in past 3 months prior * Having autoimmune disorder * On or had immunosuppressant drug(s) in past 3 months prior * Undergoing or underwent radio- and/or chemo-therapy
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry, MAHSA University
RECRUITINGJenjarum, Selangor, 42610, Malaysia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can everyday supplements boost gum disease therapy?
- Can pulling a loose tooth and putting it back save it?
- Gum fluid proteins eyed as link between smoking and periodontitis
- Gum fluid holds clues to Behçet's disease puzzle
- Magnifying the fight against gum disease: loupe vs microscope
- Can teaching people with diabetes to care for their gums also help their blood sugar?