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Can your own blood heal your gums? new study explores a natural boost for gum disease treatment

NCT ID NCT07293962

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a gel made from a patient's own blood can improve gum healing after standard deep cleaning for moderate to severe gum disease. About 14 adults with gum pockets of 5mm or deeper will receive the blood gel on one side of the mouth and a saltwater rinse on the other. Researchers will measure pocket depth, gum attachment, and bleeding over 3 months to see if the blood product helps.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 14 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have at least 20 teeth, * American Society of Anesthesiology class I or II * Periodontitis stages II-IV * Bilateral sites of deep periodontal pockets ≥5 mm Exclusion Criteria: * Limited mouth opening or symptomatic temporomandibular joint disorder * Inability to tolerate extended long periodontal treatment and/or hyperactive gag reflex * Current or former smoker or vape user * Pregnant and/or breastfeeding * Having diabetes mellitus type I or II * Having bleeding disorder or is on anticoagulants * Underwent periodontal treatment and/or surgery in past 6 months prior * Undergoing orthodontic therapy, or completed in past 3 months prior * On or had anti-inflammatory drug(s) in past 3 months prior * On or had antibiotic(s) in past 3 months prior * Having autoimmune disorder * On or had immunosuppressant drug(s) in past 3 months prior * Undergoing or underwent radio- and/or chemo-therapy

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, MAHSA University

    RECRUITING

    Jenjarum, Selangor, 42610, Malaysia

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