Periodontitis (stage 3)

Researchers compare two magnification tools, dental loupes and a dental operating microscope, during non-surgical deep cleaning for stage 3 periodontitis. Thirty adults with the disease receive scaling and root planing on different areas of the mouth, one area cleaned with loupes…

This trial tests two surgical techniques for repairing furcation defects—areas where bone loss has occurred between the roots of lower molars—in people with advanced periodontitis. One method uses a graft derived from donated skin (acellular dermal matrix), while the other uses a…

This study tests whether taking omega-3 fatty acids (fish oil) plus low-dose aspirin can improve gum disease treatment in smokers with advanced periodontitis. Participants receive these supplements or a placebo alongside standard deep-cleaning procedures. The trial measures chang…

This study tests two different bone graft materials (GTO® and GenOs®) used with a new, less invasive surgical method called NIPSA to repair bone damage from advanced gum disease. Researchers will compare how well each material helps reattach gums and fill in bone defects over 6 m…

This study tests whether a gel made from a patient's own blood can improve gum healing after standard deep cleaning for moderate to severe gum disease. About 14 adults with gum pockets of 5mm or deeper will receive the blood gel on one side of the mouth and a saltwater rinse on t…

This study tests a hydrogel wound dressing (Emanate Perio PODS) to see if it helps gums heal better after scaling and root planing, a deep cleaning for stage 3 periodontitis. 72 adults will use the gel at home twice a day for 30 minutes, or receive no extra treatment. The main go…

This study looks at whether taking probiotics (with or without vitamin B12) can improve the health of the mouth's bacteria and reduce gum disease in adults with severe periodontitis. Participants will receive standard gum treatment plus either a probiotic lozenge, a probiotic wit…