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Gum fluid holds clues to Behçet's disease puzzle

NCT ID NCT07821528

Knowledge-focused Sponsor: Gazi University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers at Gazi University are studying whether Behçet's disease, which causes mouth sores and eye inflammation, is connected to gum disease. They compare 40 people with Behçet's plus gingivitis or periodontitis against 47 people with gum disease alone. The team measures inflammatory markers in saliva and gum fluid to see if Behçet's changes the picture.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link exists, doctors might one day screen Behçet's patients for gum disease or treat gum inflammation as part of managing the condition.
What could go wrong
This small observational study cannot prove cause and effect, and any marker differences may reflect general inflammation rather than a specific connection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

87 people

The number who actually took part.

Started

Feb 2016

Finished

Feb 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The participants were divided into 4 groups; systemically healthy patients with gingivitis (HG), systemically healthy patients with periodontitis (HP), BD patients with gingivitis (BG), and BD patients with periodontitis (BP).

Ages

21 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * No systemic diseases for the controls * Aged 21 years older * A diagnosis of Behcet disease according to the diagnostic criteria * Presence at least 20 natural teeth * Ability to undergo a full mouth periodontal examination * Availability of clinical information regarding Behcet disease duration, disease activity, organ involvement, current medications Exclusion Criteria: * Other autoimmun systemic diseases * Pregnancy and lactation * Periodontal treatment within the previous 3-6 months Use of antibiotics within the previous 3 months * Fewer than 20 teeth

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Conditions

The condition(s) this trial relates to.

Behcet disease gingival disorder gingivitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Behcet syndrome Gingival diseases Periodontitis

More trials for these conditions

Other studies related to the condition(s) this trial covers.