Can pulling a loose tooth and putting it back save it?
NCT ID NCT07141680
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers test whether intentionally removing, treating, and replanting a severely loose lower front tooth works better than splinting alone. Fifty adults with advanced periodontitis and at least 50% bone loss around the tooth join the study. Half receive replantation plus splinting, half receive splinting only. The team measures gum attachment, bone levels, pocket depth, and bleeding over six months to see which approach preserves the tooth.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Intentional tooth replantation, a procedure that removes a loose tooth, cleans and root-canals it, then puts it back and splints it
- What this could lead to
- If replantation works better than splinting alone, it could offer a way to keep severely loose front teeth that would otherwise be pulled.
- What could go wrong
- The replanted tooth may not reattach firmly, may become infected, or may be lost anyway. The trial is small and follows patients for only six months, so long-term success is unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients are systemically healthy or have their systemic conditions under control. * Lower anterior incisors (42, 41, 31, 32) will be included. * Mobility classification will be Miller 3. * Radiograph showing 50% or more bone loss at the root. * Probing depth of 5 mm or more. * Bone level of adjacent teeth at ⅔ or better than the root. * Mobility of adjacent teeth will be Miller 0 or Miller 1. * The patient prefers to keep the tooth in the mouth rather than having it extracted. Exclusion Criteria: * Systemic Comorbidity * Smoking * Root Resorption * Root Fracture or Crack * Ankylosis of the Tooth
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Health Sciences, Hamidiye Faculty of Dentistry.
Istanbul, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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