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Simple blood test may predict gum treatment success

NCT ID NCT07312045

Knowledge-focused Sponsor: Ömer Faruk Okumuş Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at whether certain markers in blood and saliva can predict how well people with gum disease heal after non-surgical treatment. Researchers will measure these markers in 180 adults with healthy gums, gingivitis, or advanced periodontitis before and after treatment. The goal is to see if these markers can help identify who will respond best to therapy, potentially leading to more personalized dental care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help dentists predict which patients will respond well to gum disease treatment, leading to more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It is small and early-stage, so results may not apply to everyone or lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult individuals aged 18-65 years presenting to the periodontology clinic for routine examination or periodontal treatment. Participants will be assigned to healthy, gingivitis, or stage III/IV periodontitis groups based on periodontal diagnosis.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-65 years * Ability to provide informed consent * No systemic diseases or conditions affecting periodontal status * For Healthy Group: Probing depth ≤3 mm, no attachment loss, no radiographic bone loss * For Gingivitis Group: Gingival inflammation and bleeding on probing without attachment loss or bone loss * For Periodontitis Group: Stage III or stage IV periodontitis according to 2018 classification * No periodontal treatment within the past 6 months * Willingness to attend follow-up visits Exclusion Criteria: * Systemic diseases influencing periodontal inflammation (e.g., diabetes, autoimmune disorders) * Current pregnancy or lactation * Use of antibiotics, anti-inflammatory medications, or immunosuppressive drugs within the last 3 months * Smokers or individuals using tobacco products * History of periodontal surgery in the last 6 months * Presence of fewer than 20 natural teeth * Any condition that may interfere with study participation or data reliability

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic gingivitis gingivitis periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingivitis; chronic Periodontal diseases Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Erzincan Binali Yıldırım University Faculty of Dentistry

    RECRUITING

    Merkez, Erzincan, 24002, Turkey (Türkiye)

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