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Ibuprofen may soothe sore gums after deep cleaning, small trial hopes

NCT ID NCT07459049

Symptom relief Sponsor: University of Baghdad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking ibuprofen before a deep gum cleaning reduces pain and inflammation afterward. Thirty adults with gum disease will either get ibuprofen or a placebo. Researchers will measure inflammatory markers in the blood and pain levels using a simple scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ibuprofen
What this could lead to
If it works, this could show that taking ibuprofen before gum treatment helps reduce pain and inflammation afterward.
What could go wrong
This is a very small, early-phase trial with only 30 participants, so results may not apply to everyone. Ibuprofen also has known risks like stomach irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. systemically healthy patients. 2. having a minimum of 20 teeth. 3. Generalized unstable periodontitis. 4. Pocket depth \[≥ 4 mm\]. 5. All included participants should be adults aged more than 18 years . 6. smokers and non smokers Exclusion Criteria: 1. Allergy or hypersensitivity to Ibuprofen or other NSAIDs. 2. current systemic anti-inflammatory or antibiotic therapy (\<3 months). 3. peptic ulcer disease. 4. recent periodontal therapy (\<3 months). 5. Asthma. 6. Renal impairment . 7. Hepatic impairment. 8. Severe cardiac disease (heart failure, hypertension (. 9. Bleeding disorders (e.g., hemophilia) or patients taking anticoagulants . 10. Any participant who had known or suspected high risk for tuberculosis, hepatitis B or HIV infections. 11. pregnant or lactating females. 12. those being unable to provide written informed consent.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • College of Dentistry, University of Baghdad

    RECRUITING

    Baghdad, 10047, Iraq

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