Tiny mouth bugs linked to gum disease? new study investigates
NCT ID NCT07551115
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks how often two tiny parasites (Entamoeba gingivalis and Trichomonas tenax) are found in the mouths of people with and without gum disease. Researchers will collect spit and plaque samples from 120 adults and look at them under a microscope. The goal is to learn if these parasites are linked to worse gum health, which could help dentists in the future.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients aged 18 and older who applied to the Bolu Abant İzzet Baysal University Faculty of Dentistry, Department of Periodontology, and met the inclusion criteria.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants aged 18 years or older. * Having at least 10 natural teeth. * Willingness to undergo periodontal examination and providing written informed consent. * Includes both periodontally healthy individuals and patients with gingivitis or periodontitis. Exclusion Criteria: * Use of systemic antibiotics within the last 3 months. * Use of chlorhexidine or similar antiseptic mouthwashes within the last month. * Having received any periodontal treatment within the last 3 months. * Receiving immunosuppressive therapy or having a serious systemic immune deficiency. * Pregnancy or breastfeeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bolu Abant Izzet Baysal University, Faculty of Dentistry, Department of Periodontology
RECRUITINGBolu, Gölköy, 14030, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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