PERIODONTITIS

This study aims to find out which of two minimally invasive gum surgery techniques works better for treating bone loss caused by advanced gum disease (periodontitis). It will follow 50 patients for one year, comparing a single-flap technique to a double-flap technique. Researcher…

This study is testing if adding one of two substances—hyaluronic acid gel or a protein-rich gel called Alb-PRF—to the standard deep cleaning for gum disease leads to better results. Researchers will compare these two add-on treatments against deep cleaning alone in 51 adults with…

This study is testing whether treating severe gum disease can slow the progression of Alzheimer's disease. Researchers believe gum disease causes body-wide inflammation that may worsen Alzheimer's. The trial will enroll 70 people who have both conditions, giving half immediate gu…

This study is testing whether adding a splint (a device that connects loose teeth together) to a special deep cleaning procedure works better than the cleaning alone for people with advanced gum disease and loose front teeth. It involves 50 participants who will be randomly assig…

This study is testing whether a gel made from ferulic acid, a natural compound found in plants, can help treat gum disease (periodontitis) when used alongside a standard dental cleaning. The research involves 80 healthy adults with moderate gum disease to see if the gel reduces g…

This study is observing adults who have already had surgery for severe gum disease (periodontitis) to see how well their teeth and gums hold up over many years. Researchers are tracking two main types of surgery—one that removes diseased tissue and one that tries to regrow lost b…

This study aims to find the best way to treat severe gum disease around back teeth (molars) to prevent tooth loss. It compares two approaches: non-surgical deep cleaning versus surgical procedures that reshape or rebuild bone. The trial will follow 59 patients for five years to s…

This study is testing whether adding an injectable gel made from a patient's own blood (called i-PRF) to standard deep cleaning helps control gum disease better. In a small group of adults with periodontitis, one side of the mouth gets the gel plus cleaning, while the other side …

This study is testing whether professional dental cleaning for gum disease (periodontitis) can help control heart failure. Researchers will measure a key blood marker of heart failure in about 80 adults with both conditions over 6 months. The goal is to see if treating the gums i…

This study looks back at how well a common gum treatment called scaling and root planing (deep cleaning) works over two years. It focuses on patients with moderate to deep gum pockets. Researchers are checking if this standard treatment effectively controls gum disease in these s…

This study aims to understand how nicotine exposure in gum tissue affects the healing response after standard non-surgical treatment for periodontitis (gum disease). It will compare treatment outcomes between 56 smokers and non-smokers with gum disease. The main goal is to measur…

This study aims to understand why smokers with gum disease often heal slower after a standard dental cleaning treatment. Researchers will compare 50 people (25 smokers and 25 non-smokers) by measuring a specific healing protein in their saliva and checking their gum health before…

This study aims to understand the connection between gum disease and coronary heart disease by looking at specific genes and proteins. Researchers will measure these factors in 84 patients with gum disease, some of whom also have heart disease, before and after they receive a sta…