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Blackberry mouthwash takes on chlorhexidine in gum disease showdown

NCT ID NCT07540624

Disease control Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a blackberry extract mouthwash works as well as a standard antiseptic mouthwash (chlorhexidine) for treating gum disease. 48 adults with periodontitis will receive standard deep cleaning and then rinse with one of the mouthwashes or just plain water. Researchers will check gum health, inflammation, and bacteria levels over 3 months to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chlorhexidine gluconate mouthwash and Morus nigra (blackberry) mouthwash
What this could lead to
If it works, this could point toward a natural alternative to standard mouthwash for managing gum disease.
What could go wrong
This is a small, early-stage study with only 48 participants. The results may not apply to everyone, and the blackberry mouthwash might not be as effective as the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with periodontitis. * Systemically healthy individuals. * Patients aged between 18 and 65 years. * Presence of at least 20 natural teeth. * Volunteering to participate in the study and signing the informed consent form. Exclusion Criteria: * Presence of any systemic disease that may affect periodontal health or systemic inflammatory response (e.g., Diabetes Mellitus, immunological disorders). * Current smokers or use of any tobacco products. * Pregnancy or lactation. * Use of systemic antibiotics, anti-inflammatory drugs, or immunosuppressive medications within the last 6 months. * Having received any non-surgical or surgical periodontal treatment within the last 6 months. * Known allergy or sensitivity to chlorhexidine or Morus nigra (blackberry) extracts. * Patients using orthodontic appliances.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal disease Periodontitis

Contacts and locations

Locations

  • Inonu University Faculty of Dentistry

    Battalgazi, Malatya, 44300, Turkey (Türkiye)

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