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Can surgery save more teeth from severe gum disease?

NCT ID NCT05237401

Disease control Sponsor: King's College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two ways to treat severe gum disease that has reached the area where the roots of back teeth split. One approach uses non-surgical cleaning and maintenance, while the other involves surgery to reshape or rebuild bone. The goal is to see which method helps keep the tooth alive longer over 5 years. About 59 adults with advanced gum disease and at least one affected molar will take part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

59 people

The number who actually took part.

Started

Apr 2022

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Minimum of 12 teeth present * Diagnosis of Severe Periodontitis stage III or IV * At least one maxillary/ mandibular molar with: i) degree III horizontal furcation involvement (at least between 2 roots for maxillary molars) , ii) class B vertical furcation involvement (bone loss up to the middle third of root cones), iii) residual probing pocket depths \> 5 mm in furcation area, iv) maximum mobility degree Iand v) not already accessible for self-performed oral hygiene * Received a course of non-surgical periodontal therapy within the past six months Exclusion Criteria: Patient: * Full mouth plaque score \> 30% * A course of antibiotics within the past 3 months * Pregnant/lactating women * Relevant medical history as evaluated by the examining clinician which may have the potential to affect periodontal surgical treatment * Individuals on long-standing (2 or above years) supportive periodontal therapy (SPT) management plans Molar affected by FI: * Ongoing endodontic pathology affecting the furcation involved molar, as judged by the examining clinician * Previous periodontal surgical treatment to the furcation affected molar within the previous 5 years * Endodontically treated molar tooth without a full coverage restoration * 'Unrestorable' molar tooth (lacking adequate tooth structure to provide a restoration) as deemed by the examining clinician. * Molar tooth acting as a bridge abutment * The presence of occlusal dysfunction as assessed by the examining clinician

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Conditions

The condition(s) this trial relates to.

Furcation Defects periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Furcation defects Periodontitis Surgical procedure, unspecified

Contacts and locations

Locations

  • King's College London

    London, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.