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Gum disease breakthrough? blood concentrate shows promise in small trial

NCT ID NCT07375004

First seen Jan 29, 2026 · Last updated Jun 13, 2026 · Updated 20 times

Summary

This study tested whether adding injectable Platelet-Rich Fibrin (i-PRF), a natural concentrate from a patient's own blood, to standard deep cleaning improves gum disease outcomes. In 13 adults with moderate to severe periodontitis, one side of the mouth received the combined treatment and the other side standard cleaning alone. Researchers measured pocket depth, gum attachment, and bacterial levels over 3 months to see if i-PRF provides extra benefit.

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Contacts and locations

Locations

  • Mustansiriyah University, College of Dentistry.

    Baghdad, Iraq

Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss osteonecrosis of the jaw periodontal disorder Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.