New gum disease protocol aims to heal deep pockets
NCT ID NCT07507474
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new treatment plan called Bioperio® for people with gum disease (periodontitis). The plan includes professional teeth cleaning, oral hygiene training, and for severe cases, a special gel to help gums reattach. The goal is to close deep gum pockets and improve overall gum health. About 5,000 adults with untreated gum disease will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2023
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
adult patients diagnosed with periodontitis
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of periodontitis (proximal attachment loss in ≥2 non-adjacent teeth) * No previous treatment for periodontitis * Systemically healthy or with well-controlled chronic medical conditions * Willingness to participate in the study and comply with the follow-up schedule Exclusion Criteria: * Pregnancy or breastfeeding * Patients previously treated for periodontitis * Poorly controlled systemic conditions * Refusal to participate * Patients who did not complete the proposed treatment plan
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Pisa
RECRUITINGPisa, None Selected, 56126, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can everyday supplements boost gum disease therapy?
- Can pulling a loose tooth and putting it back save it?
- Gum fluid proteins eyed as link between smoking and periodontitis
- Gum fluid holds clues to Behçet's disease puzzle
- Magnifying the fight against gum disease: loupe vs microscope
- Can teaching people with diabetes to care for their gums also help their blood sugar?