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New gum cleaning technique tested for better periodontitis treatment

NCT ID NCT07286916

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new gum cleaning method called guided biofilm therapy (GBT) against standard deep cleaning for people with gum disease (periodontitis). 18 adults will receive either GBT or standard treatment, and researchers will measure gum pocket depth, bleeding, and biomarkers in gum fluid after 1 and 3 months. The goal is to see if GBT leads to better gum healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Guided Biofilm Therapy (Airflow Prophylaxis Master device with erythritol powder)
What this could lead to
If it works, this could offer a more effective and comfortable way to treat gum disease, potentially improving long-term gum health.
What could go wrong
This is a very small early trial with only 18 people, so results may not apply to everyone. The treatment is compared to standard care, and the benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 18 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult subjects (\>18 years). 2. Subjects are not currently under active periodontal therapy or joining other trial in the last 3 months. 3. Patients must be diagnosed with generalized unstable periodontitis with bilateral, symmetrical distribution of PPD ≥ 4mm and positive BOP. \- Exclusion Criteria: 1. Patients not diagnosed with periodontitis. 2. Patients consuming antibiotics. 3. Regular users of nonsteroidal anti-inflammatory drugs (NSAIDs). 4. Patients receiving periodontal treatment 3-months prior to the study. 5. Pregnant or mothers in a breastfeeding period. 6. Third molars and teeth with furcation involvement. 7. Patients taking antioxidant supplements. 8. Patients with heavy calculus that would prevent PerioPaper strips entrance to the periodontal pocket. 9. Patient with pulmonary diseases and with a history of allergy to erythritol. 10. Patients not willing to participate. -

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • College of Dentistry, University of Baghdad

    RECRUITING

    Baghdad, 10047, Iraq

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