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Gum surgery breakthrough? new technique saves healing tissue

NCT ID NCT05533528

Disease control Sponsor: Universidad de Murcia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new surgical method for treating advanced gum disease. Instead of removing all inflamed tissue, the surgeon preserves the granulation tissue (the body's natural healing tissue) to see if it leads to better gum attachment and less bleeding. The trial involves 50 people with stage III or IV periodontitis who still have deep gum pockets after non-surgical treatment. Participants are randomly assigned to either the new technique or standard surgery, and results are checked after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
periodontal surgery (modified surgical protocol with granulation tissue preservation)
What this could lead to
If successful, this could lead to a better surgical technique for treating gum disease, potentially improving healing and reducing the need for more invasive procedures.
What could go wrong
This is a small, early-stage trial with only 25 participants per group, so results may not apply to everyone. The new technique may not be significantly better than the standard approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Stage III or IV periodontitis, including all grades. * Unresolved deep pockets (probing pocket depth \[PPD\] \>5 mm + BoP) 4 to 6 weeks after non-surgical treatment. * Interproximal plaque index \<35% maintained during periodontal treatment and maintenance. * Adherence to periodontal maintenance appointments. Exclusion Criteria: * Systemic disease contraindicating periodontal surgery. * Teeth with incorrect endodontic treatment or restoration. * Stage I or II periodontitis.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal bone loss Periodontal diseases Periodontal pocket

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centro Odontologico Del Sureste Slp

    RECRUITING

    Murcia, 30007, Spain

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