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Can a light zap improve gum health in obesity?

NCT ID NCT06073704

Disease control Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a special light treatment (antimicrobial photodynamic therapy) to standard deep cleaning helps people with obesity and gum disease. 24 participants will receive either standard cleaning alone or cleaning plus the light therapy. Researchers will check gum health and measure inflammation markers at 1, 3, and 6 months to see if the light treatment makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
antimicrobial photodynamic therapy (aPDT) - a light-based treatment applied after deep cleaning of the gums
What this could lead to
If it works, this could offer a simple, drug-free way to improve gum health in people with obesity, who often have worse outcomes from standard treatment.
What could go wrong
This is a very small early-stage trial with only 24 participants, so results may not apply to everyone. The added benefit of the light therapy over standard cleaning alone may be small or none.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Obesity (grade II and III classified according to Body Mass Index) * Periodontitis stage II to IV * Presence of at least 20 teeth excluding 3rd molars. Exclusion Criteria: * Smokers * Alcohol or drugs consumption * Kidney disorders * Pregnancy or lactation * Use of antibiotics at the last 30 days * Use of drugs that alter periodontal structures as phenytoin or ciclosporin * Periodontal treatment at the last 6 months

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bauru School of Dentistry

    RECRUITING

    Bauru, São Paulo, 17012-901, Brazil

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