Washington University School Of Medicine
Clinical trials sponsored by Washington University School Of Medicine, explained in plain language.
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DNA vaccine aims to train body to fight breast cancer
⭐️ VACCINE ⭐️ OngoingThis early-stage study tests whether a DNA vaccine that targets a protein called mammaglobin-A (found on many breast cancer cells) is safe for people with ER+, HER2- breast cancer. The vaccine is given alongside standard hormone therapy or chemotherapy before surgery. The study i…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:23 UTC
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New drug cocktail aims to spare transplant patients from chemo
Disease control OngoingThis study tests a combination of two drugs, polatuzumab vedotin and rituximab, as a first treatment for a rare cancer called post-transplant lymphoproliferative disorder (PTLD) that can occur after an organ or stem cell transplant. The goal is to see if this combo is safe and ef…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jul 01, 2026 23:00 UTC
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Supercharged immune cells aim to beat back tough leukemia
Disease control OngoingThis phase 2 trial tests whether giving patients with hard-to-treat acute myeloid leukemia (AML) a special type of immune cell—called a cytokine-induced memory-like natural killer (NK) cell—after a stem cell transplant can improve their chances of staying cancer-free. About 60 ad…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Surgery may give paralyzed patients a helping hand
Disease control OngoingThis study tests whether nerve transfer surgery can improve arm and hand function in people with complete spinal cord injuries who have no hand movement. Seventy participants will undergo surgery followed by 48 months of occupational therapy. The goal is to help them regain indep…
Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Triple drug cocktail targets tough lung cancer
Disease control OngoingThis pilot study tests a combination of three drugs—zimberelimab, domvanalimab, and etrumadenant—in 30 adults with advanced non-small cell lung cancer who have already been treated with immunotherapy. The goal is to see if the triple therapy is safe and can shrink tumors. The stu…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Can a common Alzheimer's drug prevent delirium relapse in poisoning patients?
Disease control TerminatedThis study tests whether rivastigmine, a drug used for Alzheimer's, can prevent delirium from coming back after initial treatment with physostigmine for anticholinergic poisoning. About 42 people aged 10 and older with controlled delirium will receive either rivastigmine or a pla…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Immune-Guiding antibody aims to clean up remaining cancer cells after transplant
Disease control OngoingThis early-phase study tests whether adding mosunetuzumab after a stem cell transplant is safe for people with aggressive B cell lymphoma that has come back or not responded to prior treatments. Mosunetuzumab is an engineered antibody that helps the body's T cells recognize and k…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can money skills and mentors shield AIDS orphans from HIV?
Disease control OngoingThis study compares two methods of rolling out a program called Bridges, which gives financial literacy training and one-on-one mentors to 1,440 teens aged 11-17 who lost parents to AIDS in Uganda. The goal is to see which approach works better at reducing HIV risk and improving …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New pill shows promise for rare skin cancer in early trial
Disease control OngoingThis early-phase trial tests a new drug called tulmimetostat (DZR123) in 24 people with advanced mycosis fungoides or Sézary syndrome, rare types of skin lymphoma. Participants must have tried at least one prior treatment. The study aims to see if the drug is safe and tolerable, …
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Could less radiation be better? new trial spares healthy neck tissue
Disease control OngoingThis phase 2 trial tests whether it is safe to skip radiation on one or both sides of the neck that show no signs of cancer after surgery. The goal is to reduce side effects like dry mouth and trouble swallowing without increasing the chance of cancer returning. The study include…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Phone app aims to lift depression and boost HIV treatment in teens
Disease control OngoingThis study is testing a mobile app called Suubi-Mhealth for Ugandan teens aged 14-17 who have both HIV and depression. The app uses cognitive-behavioral therapy (CBT) to help improve mood and make it easier to stick with HIV medication. About 248 teens will take part to see if th…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Custom-Made vaccine targets deadly brain cancer in tiny pilot trial
Disease control OngoingThis early-stage trial tested a personalized DNA vaccine designed to train the immune system to attack glioblastoma, a fast-growing brain cancer. Nine patients with a specific type of glioblastoma (unmethylated MGMT) received the vaccine along with an immune booster. The main goa…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New combo therapy aims to slow deadly pancreatic cancer
Disease control OngoingThis study tests whether adding a drug called defactinib to targeted radiation therapy can help control advanced pancreatic cancer better than radiation alone. About 42 people with inoperable pancreatic cancer will take part. The goal is to see if the combination slows cancer gro…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Could one radiation dose be enough for early breast cancer?
Disease control OngoingThis study tests whether a single, focused radiation treatment works as well as five treatments for people with low-risk stage 0 or I breast cancer after a lumpectomy. About 134 participants will be randomly assigned to receive either one or five doses of radiation to the tumor a…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New vaccine targets aggressive brain tumors in early trial
Disease control OngoingThis early-phase study tests a personalized DNA vaccine designed to target unique markers on a person's glioblastoma (a fast-growing brain cancer). The vaccine is given along with an immunotherapy drug (retifanlimab) that helps the immune system attack the tumor. The study includ…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Immunotherapy boosts chemo in aggressive breast cancer trial
Disease control OngoingThis study tests whether adding the immunotherapy drug nivolumab to standard chemotherapy before surgery can help the immune system fight triple-negative breast cancer more effectively. About 15 people with early-stage (stage II or III) triple-negative breast cancer will receive …
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Engineered donor cells take aim at tough blood cancers in early trial
Disease control OngoingThis early-phase trial tests a new type of immune cell therapy called WU-CART-007 for people with certain blood cancers, including acute myeloid leukemia and T-cell lymphoma, that have come back or not responded to treatment. The therapy uses donor cells that are genetically modi…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New cocktail aims to tame incurable head and neck cancer
Disease control OngoingThis study tests a three-drug combination called CACTUX (cisplatin, nab-paclitaxel, and cetuximab) in 74 people with head and neck cancer that cannot be cured. The goal is to see if this mix works better and causes fewer side effects than the standard treatment. Participants have…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Precision radiation boost aims to tame High-Risk prostate cancer
Disease control OngoingThis study tests a precise radiation technique called adaptive SBRT for men with high-risk or unfavorable intermediate-risk prostate cancer. The treatment targets the prostate and pelvic lymph nodes while giving an extra radiation boost to tumor spots seen on MRI. The goal is to …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Can two old drugs turn back the clock on aging in mental illness?
Disease control OngoingThis study tests whether a combination of dasatinib and quercetin, two drugs that clear out aging cells, can safely slow down accelerated aging in older adults with treatment-resistant depression or schizophrenia. Forty participants aged 50 and older will take the drugs and be mo…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New three-step combo targets tough head and neck cancers
Disease control OngoingThis study tests a three-step treatment plan for people with a type of head and neck cancer not caused by HPV. First, patients take a drug called palbociclib before standard chemoradiation, then receive chemoradiation, and finally take palbociclib again after treatment. The goal …
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New combo therapy shows promise in early sarcoma trial
Disease control OngoingThis study tests a new drug (ADI-PEG 20) combined with chemotherapy and radiation before surgery for soft tissue sarcoma. The goal is to find the safest dose and see how well it shrinks tumors. Only 6 patients with intermediate or high-grade sarcoma of the trunk or limbs are taki…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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Experimental chemo combo aims to boost transplant success in MDS
Disease control OngoingThis early-phase study tests CPX-351 (Vyxeos), a two-drug chemotherapy, in 20 adults aged 18-70 with higher-risk myelodysplastic syndrome (MDS) who are eligible for a stem cell transplant. The main goal is to see if the drug is safe and tolerable, with secondary goals of measurin…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Lung cancer patients get new hope with Arginine-Starving drug combo
Disease control OngoingThis study tests a three-drug combination (ADI-PEG 20, gemcitabine, and docetaxel) in people with lung cancer that has worsened after initial treatment. The goal is to find the safest dose and see if the combination can shrink tumors or slow disease progression. About 31 particip…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Blood-filtering therapy may slow lung decline in transplant patients
Disease control OngoingThis phase 3 trial tests a treatment called extracorporeal photopheresis (ECP) for lung transplant patients who develop bronchiolitis obliterans syndrome (BOS), a form of chronic rejection. ECP involves filtering a patient's blood, treating it with a light-sensitive drug, and ret…
Phase: PHASE3 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Cancer drug cabozantinib takes on rare, Fast-Growing tumors
Disease control OngoingThis phase 2 trial tests the drug cabozantinib in 35 people with high-grade neuroendocrine tumors that have worsened after at least one prior treatment. These are rare, fast-growing cancers with limited options. The study aims to see if cabozantinib can shrink tumors or slow thei…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Can 'Zombie Cell' cleaners fight Alzheimer's? new trial tests idea
Disease control OngoingThis phase 2 trial is testing whether a combination of two drugs, dasatinib and quercetin, is safe and feasible for people with early-stage Alzheimer's or mild cognitive impairment. The drugs aim to clear aging 'senescent' cells that may contribute to brain damage. 48 participant…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New drug combo aims to boost immunotherapy for head and neck cancer
Disease control OngoingThis phase 2 trial tests whether adding ramucirumab to pembrolizumab (Keytruda) works better than pembrolizumab alone for people with PD-L1 positive head and neck cancer that has come back or spread. About 37 participants will receive either the combination or the single drug. Th…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Robots vs. surgeons: can a machine improve knee replacement outcomes?
Disease control OngoingThis study tests whether robot-assisted knee replacement surgery leads to better results than traditional manual surgery for people with knee osteoarthritis. About 95 participants will receive the robot-assisted procedure and use a special knee brace to track motion. Researchers …
Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Can a cochlear implant beat a hearing aid for kids with one-sided deafness?
Disease control OngoingThis study compares cochlear implants to hearing aids in 80 children aged 4 to 14 with hearing loss in one ear. Researchers measure how well kids understand speech and hear in noise before and after getting an implant. The goal is to see if the implant provides better hearing tha…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New drug combo shows promise for Hard-to-Treat brain cancer
Disease control OngoingThis early-phase study tests a combination of two drugs, acalabrutinib and durvalumab, in people with primary central nervous system (CNS) lymphoma—a rare and aggressive brain cancer. The study includes up to 25 patients whose cancer has returned after prior treatment or who cann…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a new drug stop inherited Alzheimer's in its tracks?
Disease control OngoingThis study tests lecanemab, an antibody that targets amyloid plaques in the brain, in 40 people who carry a gene mutation that causes early-onset Alzheimer's. Participants previously received another anti-amyloid drug and will now receive lecanemab to see if it can fully clear am…
Phase: PHASE3 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Can a Nutrient-Packed supplement boost baby brain development and prevent early birth?
Disease control OngoingThis study tests whether a special food supplement with added omega-3s and choline can help undernourished pregnant women carry their babies longer and improve their babies' brain development. It also tests a simple talk therapy program to reduce depression during and after pregn…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Which shoulder surgery is better for arthritis? new study aims to find out
Disease control ENROLLING_BY_INVITATIONThis study compares two types of shoulder replacement surgery for people with glenohumeral osteoarthritis: hemiarthroplasty with a pyrocarbon implant and total shoulder arthroplasty. Researchers will track 74 participants for 10 years to see which surgery provides better pain rel…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Milder stem cell transplant shows promise for kids with immune disorders
Disease control OngoingThis study tests a stem cell transplant using a milder chemotherapy-like regimen to treat children and young adults (up to age 28) with various immune system disorders. The goal is to help the donor stem cells settle in the body with fewer side effects. The study involves 20 part…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can new drugs delay inherited Alzheimer's? major trial underway
Disease control OngoingThis study tests whether experimental drugs can slow down memory and thinking problems in people who have a gene mutation that causes Alzheimer's disease. About 490 adults aged 18-80 with this genetic risk are taking either a study drug or a placebo. The goal is to see if the dru…
Phase: PHASE2, PHASE3 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New drug combo aims to halt Alzheimer's in people with genetic mutation
Disease control OngoingThis study tests whether two drugs, E2814 and lecanemab, can slow the progression of Alzheimer's in people who carry a gene mutation that causes the disease. About 197 participants will receive either the drugs or a placebo over 2 to 4 years. Researchers will measure changes in t…
Phase: PHASE2, PHASE3 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Can a pill make CAR T-Cells last longer?
Disease control OngoingThis early-phase trial tests whether the drug duvelisib can help CAR T-cells persist longer in people with non-Hodgkin lymphoma or acute lymphocytic leukemia. About 42 adults who have already received a standard CAR T-cell therapy will take duvelisib pills daily. The main goal is…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Double transplant strategy targets tough lymphoma
Disease control OngoingThis phase 2 study tests a two-step transplant approach for people with high-risk non-Hodgkin's lymphoma. First, patients receive a transplant using their own stem cells, followed by a second transplant from a donor. The goal is to improve long-term disease control. The trial enr…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New hope for chronic leg pain: catheter procedure could reduce Post-Clot disability
Disease control OngoingThis study tests whether a catheter-based procedure can reduce the severity of post-thrombotic syndrome (PTS) — a painful, long-term leg condition that can follow a deep vein clot. About 225 adults with disabling PTS and a blocked iliac vein will receive either the procedure plus…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Could group prenatal care help moms with diabetes?
Disease control OngoingThis study tests whether group prenatal care, where women with diabetes meet together with a healthcare provider, works better than standard one-on-one visits. Researchers will track blood sugar levels and weight after delivery in 117 pregnant women with type 2 or gestational dia…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New combo therapy aims to stall lung cancer progression
Disease control OngoingThis study tests whether adding the experimental drug APL-101 to standard osimertinib can better control EGFR-mutated metastatic non-small cell lung cancer. About 27 adults who have already started osimertinib without their cancer getting worse will receive the combination until …
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New combo therapy shows promise for rare, aggressive skin cancer
Disease control OngoingThis study tests giving the chemotherapy drug paclitaxel before and during radiation therapy for people with cutaneous angiosarcoma, a rare and aggressive skin cancer. The goal is to shrink the tumor before surgery and improve how long patients live without the cancer coming back…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New drug cocktail aims to keep relapsed myeloma in check
Disease control OngoingThis phase II study tests whether a combination of elotuzumab, pomalidomide, and dexamethasone can help control relapsed multiple myeloma after a second stem cell transplant. The trial enrolls 25 adults whose myeloma returned after their first transplant. Participants receive the…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Weight-Loss drug plus IUD aimed to save uteruses – but trial never started
Disease control TerminatedThis study planned to test whether combining the weight-loss drug semaglutide with a hormone-releasing IUD could reverse endometrial hyperplasia (a precancerous condition) in premenopausal women with obesity, allowing them to keep their uterus. The trial was withdrawn before enro…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Money smarts may boost HIV med adherence in ugandan teens
Disease control OngoingThis study tested whether giving HIV-positive teens in Uganda access to savings accounts, financial training, and mentorship helps them take their HIV medication regularly. 702 teens aged 10-16 from 40 clinics took part. The goal was to see if economic stability can improve treat…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can money skills and peer support help teens beat HIV? new study tests four tools together.
Disease control OngoingThis study tests four different support tools—financial literacy training, matched savings accounts, a cartoon-based adherence guide, and role models with HIV—to see which combination best helps youth aged 11-17 in Uganda stay on their HIV medication and keep the virus undetectab…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Money and parenting skills may curb child behavior problems in uganda
Disease control OngoingThis study tests whether helping families with money and parenting skills can improve behavior in children ages 10-14 with oppositional defiant or conduct disorder. About 900 children and their caregivers in Uganda will be split into three groups: one gets financial help, one get…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New immunotherapy combo shows promise for Tough-to-Treat lymphoma
Disease control OngoingThis early-phase trial is testing whether adding the immunotherapy drug mosunetuzumab to standard chemotherapy can safely treat aggressive B-cell lymphoma that has come back or not responded to treatment. About 24 adults will receive either DHAX or ICE chemotherapy plus mosunetuz…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New combo therapy aims to fight inoperable uterine cancer
Disease control OngoingThis early-phase trial tests whether adding an immune-boosting drug (TSR-042) to standard radiation therapy is safe and effective for people with inoperable endometrial cancer. Ten participants with early-stage disease will receive both treatments. The goal is to see if the combi…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New combo shows promise for tough head and neck cancers
Disease control OngoingThis study tested a combination of two drugs—nab-paclitaxel (a chemotherapy) and nivolumab (an immunotherapy)—in 46 people with advanced head and neck cancer that had stopped responding to a prior immunotherapy. The goal was to see if the combo could shrink tumors or slow the can…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New drug cocktails aim to beat river blindness
Disease control OngoingThis study tests four different drug combinations in 300 adults with onchocerciasis (river blindness), a parasitic disease. Participants first receive ivermectin to clear skin and eye parasites, then get one of the new combos. The goal is to see which combo is safest and most eff…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New drug duo shows promise against common lymphoma
Disease control OngoingThis study tests a combination of two drugs, mosunetuzumab and polatuzumab vedotin, in people with untreated follicular lymphoma. The drugs work together to help the immune system find and kill cancer cells. The goal is to see how many patients achieve a complete response, meanin…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a nutrient in eggs keep malnourished kids from getting worse?
Disease control OngoingThis study tests whether adding choline (a nutrient found in eggs and meat) to a standard food supplement helps children with moderate acute malnutrition avoid becoming severely malnourished. About 1,500 children aged 6 to 59 months in Malawi will receive either the standard supp…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New drug combo shows promise in shrinking breast tumors before surgery
Disease control OngoingThis study tests whether adding a targeted drug (PD 0332991) to standard hormone therapy (anastrozole) before surgery can better stop breast cancer cell growth in women with early-stage ER+ HER2- breast cancer. About 84 women with stage 2 or 3 disease will receive the combination…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a Lab-Made protein restore immune defenses in glioma patients?
Disease control OngoingThis early-phase trial tests whether a drug called rhIL-7-hyFc can safely increase lymphocyte counts in people with high-grade glioma who have low immune cells after standard radiation and chemotherapy. About 42 participants will receive either the drug or a placebo by injection.…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New drug cocktail aims to shrink Hard-to-Treat sarcomas
Disease control OngoingThis study tests whether adding two immunotherapy drugs (nivolumab and ipilimumab) to the targeted therapy cabozantinib can shrink tumors better than cabozantinib alone in people with metastatic soft tissue sarcoma. About 105 adults whose cancer has worsened after prior treatment…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New drug cocktail aims to keep myeloma in check after transplant
Disease control OngoingThis study tests a three-drug combination (ixazomib, lenalidomide, and dexamethasone) given after a stem cell transplant to people with multiple myeloma. The goal is to see if this treatment can keep the cancer away longer. After four rounds, participants are randomly assigned to…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New drug cocktail aims to shrink head and neck tumors
Disease control OngoingThis study tests a combination of three drugs (olaparib, pembrolizumab, and carboplatin) as a first treatment for people with head and neck cancer that has come back or spread. The goal is to see if this mix works better than the standard treatment at shrinking tumors. About 30 a…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Custom-Made vaccine plus immunotherapy shows promise in tough lung cancer
Disease control OngoingThis study tests a personalized vaccine (made from each patient's unique tumor markers) combined with the immunotherapy drug durvalumab for people with extensive-stage small cell lung cancer. The goal is to see if this combination is safe and can help slow cancer growth. Only 6 p…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Could a 'Use-When-Needed' inhaler help teens with asthma?
Disease control OngoingThis study tests whether a symptom-driven inhaler (budesonide/formoterol) works better for teens with asthma who often forget their daily maintenance inhalers. Researchers will compare adherence and asthma flare-ups between the standard daily inhaler plus rescue inhaler group and…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 26, 2026 18:15 UTC
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Could using an inhaler only when needed beat daily asthma pills?
Disease control OngoingThis study looks at whether people with asthma who often forget to take their daily maintenance inhaler might do better using an inhaler only when they have symptoms. Researchers will compare adherence and asthma flare-ups between two groups: one continuing daily maintenance inha…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 26, 2026 18:12 UTC
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Chemotherapy delivered directly to abdomen shows promise in early trial
Disease control OngoingThis early-phase trial tests a combination of three drugs for people whose appendix or colon cancer has spread to the lining of the abdomen (peritoneal carcinomatosis). After surgery to remove visible tumors, patients receive chemotherapy directly into the abdomen (oxaliplatin) p…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 26, 2026 18:01 UTC
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New PET tracer aims to spot Alzheimer's plaques safely
Diagnosis OngoingThis study tests a new radioactive tracer called Fluselenamyl for PET scans to detect beta-amyloid plaques in the brain, a hallmark of Alzheimer's disease. Researchers will check its safety and how well it works in 60 healthy volunteers and people with mild cognitive impairment o…
Sponsor: Washington University School of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 13:05 UTC
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Scientists test new imaging to see muscle pain clearly
Diagnosis OngoingThis study aims to develop new imaging methods to better detect and understand myofascial pain, a common muscle pain condition. Researchers will compare 52 participants—some with myofascial pain and some healthy—using MRI, muscle electrical activity, and fiber-optic imaging. The …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Beats over blood pressure: music campaign aims to prevent stroke in nigeria
Prevention OngoingThis study tests whether a music-inspired community campaign, called Music4Health, can help lower blood pressure and improve stroke awareness among 1,412 youth (ages 14-24) and their caregivers (ages 40+) in Nigeria. Participants will take part in listening sessions and activitie…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jul 01, 2026 23:00 UTC
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Can Youth-Led HIV testing programs last? new study aims to find out
Prevention OngoingThis study looks at how to keep a youth-friendly HIV self-testing program called 4YBY running in Nigeria. It will involve over 1,200 young people aged 14-24 who are at risk for HIV. Researchers will compare standard program delivery with an enhanced version that includes extra su…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jul 01, 2026 23:00 UTC
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Could a bone drug make dense breasts less Cancer-Prone?
Prevention OngoingThis phase 2 trial tests whether denosumab, a drug that blocks RANKL signaling, can reduce mammographic breast density in premenopausal women with dense breasts. Dense breasts are a known risk factor for breast cancer. The study involves 210 women who will receive either denosuma…
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jun 27, 2026 12:02 UTC
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New community effort aims to slash HPV risk in nigerian families
Prevention OngoingThis study tests a community-driven campaign to increase HPV prevention among mother-daughter pairs in Nigeria. About 1,838 participants will take part in events and surveys. The goal is to get more girls vaccinated against HPV and more mothers to self-test for the virus, which c…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jun 27, 2026 09:01 UTC
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New program aims to heal war trauma passed down in refugee families
Symptom relief OngoingThis study tests a program that combines family group sessions with a virtual peer mentoring program for US-born teens (ages 14-17) whose parents resettled as refugees. The goal is to reduce symptoms of PTSD, depression, anxiety, and behavior problems caused by intergenerational …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Proton beam therapy may offer gentler radiation for esophageal cancer
Symptom relief OngoingThis study looks at whether proton beam therapy, a precise form of radiation, causes fewer severe side effects than standard radiation for people with esophageal cancer. About 22 patients with stage II or III esophageal cancer will receive proton therapy and report their symptoms…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Memory boot camp for Parkinson's: new study tests brain training
Symptom relief OngoingThis study tests two types of memory training in 120 people with Parkinson's disease and mild cognitive impairment. Participants complete 8 weekly sessions of either process or strategy training. The goal is to see if these exercises improve remembering to do tasks in daily life,…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Can a 6-Week zoom therapy help kids at risk for depression? st. louis schools test new approach
Symptom relief ENROLLING_BY_INVITATIONThis study tests a 6-8 week caregiver-child therapy called THRIVE, delivered by school counselors via video or in school, to improve emotional and behavioral health in children aged 3-7 who are near the clinical threshold for mental health problems. THRIVE is compared to an onlin…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New painkiller aims to cut opioid use after shoulder surgery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a medication applied directly during shoulder replacement surgery (ZYNRELEF) can reduce the need for strong painkillers after the operation, compared to the standard method of using a nerve block with a catheter. About 86 adults having shoulder replacemen…
Phase: PHASE4 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Tuning in: personalized music may soothe kids after surgery
Symptom relief OngoingThis study tests whether playing a child's favorite music before and during ear tube surgery can reduce confusion and agitation when they wake up. Researchers will enroll 160 children ages 3 to 9. The goal is to see if personalized music makes recovery smoother and less distressi…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Group prenatal care may ease depression and prevent preterm birth in black mothers
Symptom relief OngoingThis study tests a group prenatal care program called EleVATE GC for African-American women at high risk for postpartum depression. The program aims to reduce depression, preterm birth, and low birthweight by providing support and addressing stress. Researchers will compare outco…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New recovery protocol aims to speed healing after bladder surgery in kids
Symptom relief OngoingThis study is testing whether a standardized care plan called Enhanced Recovery After Surgery (ERAS) can help children and young adults recover faster after urologic reconstructive surgery. The plan includes steps before, during, and after surgery to improve pain control and shor…
Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Could laughing gas help stop suicidal thoughts?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether inhaling nitrous oxide (laughing gas) can quickly reduce suicidal thoughts in people hospitalized for depression. Fifty adults with major depression and active suicidal ideas will receive either nitrous oxide or a placebo gas, plus their usual treatment. …
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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AI-Guided radiation may shield ovaries in young cancer patients
Knowledge-focused OngoingThis study tests whether a new type of adaptive radiotherapy can reduce radiation exposure to the ovaries in young women (ages 18-50) receiving pelvic radiation for cancers like uterine, rectal, or cervical cancer. Using advanced imaging and an AI treatment planning system, resea…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jul 01, 2026 23:00 UTC
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Scientists dive into bone marrow to unlock vaccine memory secrets
Knowledge-focused OngoingThis study looks at how the immune system 'remembers' vaccines by tracking special cells in the bone marrow. Twenty-five healthy adults will receive four different vaccines at once and give blood, bone marrow, and lymph node samples over two years. The goal is to understand why s…
Phase: PHASE4 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jul 01, 2026 23:00 UTC
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Study probes whether exercise and meditation shield aging brains from stress damage
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 468 older adults who previously took part in a trial of mindfulness and exercise. Researchers will measure how these lifestyle changes affect memory, emotional health, and biological markers of Alzheimer's risk. The goal is to understand how stress impacts the …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Peanut butter meals could keep ghanaian kids in class
Knowledge-focused OngoingThis study looks at whether giving schoolchildren in rural Ghana a daily peanut-based meal can improve school attendance and reduce dropouts. About 5,800 kids aged 5 to 17 will receive either the peanut meal or a local rice/millet flour meal. The goal is to see if the peanut opti…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Radioactive tracer reveals tau tangles in Alzheimer's brains
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a new radioactive compound called F 18 T807 that lights up tau tangles in the brain during a PET scan. Researchers want to see if the amount of tau relates to memory and thinking problems in people with a rare, inherited form of Alzheimer's disease. About 130 adu…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Sleep disorder study could pave way for Parkinson's prevention
Knowledge-focused ENROLLING_BY_INVITATIONThis study enrolls 500 adults with a sleep condition called REM sleep behavior disorder (RBD), which often leads to Parkinson's disease or related brain disorders. Researchers will track symptoms like thinking, movement, and smell to develop a rating scale. The goal is to prepare…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Brain scans may reveal how to protect memory during radiation
Knowledge-focused OngoingThis study follows 71 glioma patients before and after radiation therapy to see how their thinking skills change. Researchers use special brain scans (RS-fMRI) to map which brain networks are most harmed by radiation. The goal is to learn which areas to avoid during treatment pla…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Brain scans aim to unlock dementia mystery in Parkinson's
Knowledge-focused OngoingThis study uses a special brain scan called PIB PET to look at different types of dementia in people with Parkinson's disease. The goal is to find out who might develop dementia and what causes it. Researchers will study 320 participants to better understand these brain changes.
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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AI alerts for surgery patients: study pulled before it began
Knowledge-focused TerminatedThis study planned to test whether giving doctors machine-learning alerts about patient risks after surgery could reduce serious complications like kidney injury or unplanned ICU stays. It was designed for high-risk patients, but the study was withdrawn before enrolling anyone, s…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New PET tracers tested to spot Alzheimer's tau tangles
Knowledge-focused OngoingThis study tests three new imaging agents (18F-RO948, 18F-MK6240, and 18F-GTP1) to see how well they detect tau protein buildup in the brains of people with Alzheimer's disease compared to healthy older adults. About 38 participants aged 50-100 will receive PET scans to compare t…
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Pregnant? your sleep could shape your heart health
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at sleep health in 50 low-income pregnant women. Researchers will use a home sleep test and a wrist activity monitor to measure sleep. They want to see how sleep relates to heart health and social factors. The goal is to create better sleep screening and treatmen…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Lung cancer showdown: surgery or radiation – which is better?
Knowledge-focused OngoingThis study follows 446 people with stage I non-small cell lung cancer who chose either surgery or stereotactic body radiation therapy (SBRT). Researchers will track cancer recurrence, survival, and quality of life for up to 3 years to see which treatment offers better outcomes. T…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New brain scan may uncover Inflammation's role in Parkinson's
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether small amounts of brain inflammation contribute to movement and thinking problems in people with Parkinson disease. Researchers will use a new radioactive tracer called [11C]-CS1P1 in PET scans to measure inflammation in the brain. The study includes 80…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Diet vs. surgery: which weight loss method changes metabolism more?
Knowledge-focused OngoingThis study looks at how the body handles different types of meals after losing about 16-18% of body weight through either a low-calorie diet or gastric bypass surgery. Researchers will measure insulin, blood sugar, fats, and other markers in 30 adults with obesity but without dia…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Scientists investigate skin immune cells to understand Graft-Versus-Host disease
Knowledge-focused OngoingThis study looks at how different types of immune cells in the skin, called dendritic cells, are involved in graft-versus-host disease (GVHD) after a bone marrow transplant. Researchers will take small skin samples and blood from 22 adults with acute or chronic skin GVHD. The goa…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Should you know your Alzheimer's odds? new study weighs the impact
Knowledge-focused OngoingThis study looks at what happens when healthy older adults learn their personal five-year risk of developing Alzheimer's dementia. Researchers are giving 450 participants their risk estimates at different times and tracking changes in mood, thinking, and distress. The goal is to …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study aims to predict Crohn's treatment success with scans and blood tests
Knowledge-focused OngoingThis study looks at 112 people with small bowel Crohn's disease who are starting a new biologic therapy. Researchers use MRI scans and blood protein tests to see if they can predict who will achieve remission without steroids after one year. The goal is to help doctors choose the…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can a lab test predict which chemo works best? new study aims to find out
Knowledge-focused OngoingThis study looks at whether testing cancer cells in a lab can predict how well chemotherapy will work for people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Researchers will take blood and bone marrow samples before and during treatment to see if lab res…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Which diet wins? study tests mediterranean, Low-Carb, and Plant-Based plans on obesity
Knowledge-focused OngoingThis study looks at why some people with obesity develop conditions like type 2 diabetes while others don't. Researchers are comparing three popular diets—Mediterranean, low-carb, and very-low-fat plant-based—in 180 participants to see how they affect insulin sensitivity and over…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Brain blood flow secrets revealed by breathing test
Knowledge-focused ENROLLING_BY_INVITATIONThis study uses MRI scans to see how the brain's blood vessels react when people breathe in extra carbon dioxide. Researchers want to compare healthy adults and those with brain blood vessel diseases. The goal is to learn more about brain blood flow and oxygen use, which could he…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Brain wave clues may unlock ECT success in tough depression cases
Knowledge-focused OngoingThis study looks at whether brain wave patterns recorded during and after electroconvulsive therapy (ECT) can predict how much depression symptoms improve. About 31 adults with treatment-resistant depression will have their brain activity measured with a wearable EEG device. The …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Ear-Zap study sees if nerve stimulation is safe for kids
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether a device that gently stimulates a nerve in the ear is safe and tolerable for healthy children. Ten children will receive a single 30-minute session while their heart rate, oxygen levels, and brain waves are monitored. The goal is to learn how the sti…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Cancer consent study pulled before it began
Knowledge-focused TerminatedThis study was designed to test whether adding a simple visual summary page to standard consent forms helps cancer patients better understand what they are signing up for and feel less anxious. It planned to enroll adults with cancer who were already joining other clinical trials…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Personalized risk reports may boost lung cancer screening and smoking cessation
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether giving smokers and former smokers a personalized risk report (based on clinical and genetic factors) helps doctors order lung cancer screening and helps patients follow through. About 915 participants will be randomly assigned to usual care or one of two …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Vitamin D's secret role in blood pressure revealed?
Knowledge-focused OngoingThis study looks at how vitamin D levels might influence high blood pressure in people with type 2 diabetes. Researchers will collect blood samples from 40 participants to study immune cells called monocytes and see if they trigger a hormone that raises blood pressure. The goal i…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can your genes predict prostate cancer spread?
Knowledge-focused OngoingThis study follows nearly 2,000 men with newly diagnosed prostate cancer to see if certain genes increase the risk of the cancer spreading. Researchers will analyze genetic markers to better predict who might face more aggressive disease. The goal is to improve early detection of…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Gene test could guide leukemia treatment after chemo
Knowledge-focused OngoingThis study looks at whether checking for leftover leukemia-related gene mutations after initial chemotherapy can help predict relapse and survival in adults with acute myeloid leukemia (AML). Researchers will follow 107 patients aged 18-60 who are in remission after chemo. Those …
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Online prep program for head & neck surgery patients fails to launch
Knowledge-focused TerminatedThis study aimed to see if a personalized online education program could help people having major head or neck surgery feel more prepared and satisfied, and reduce trips to the hospital. The study was withdrawn before any participants were enrolled, so no results are available.
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Postpartum depression study combining ketamine and therapy withdrawn before starting
Knowledge-focused TerminatedThis study was designed to see if combining low-dose ketamine injections with interpersonal therapy could help improve mood in low-income women after a C-section. The researchers planned to enroll 0 participants and the study was withdrawn before it began. No results are availabl…
Phase: PHASE2, PHASE3 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Fat storage secrets: why some stay healthy despite obesity
Knowledge-focused OngoingThis study looks at why storing fat around organs like the liver affects some people's health more than others. Researchers will measure insulin sensitivity and inflammation in 144 lean and obese adults. The goal is to find better ways to treat diseases like diabetes and heart di…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Teen migraine mystery: do puberty hormones fuel the pain?
Knowledge-focused OngoingThis study explores how sex hormones (like testosterone and estrogen) during puberty relate to migraine pain and sensitivity in adolescents aged 11-15. Researchers will test pain responses and track migraine disability in 100 teens with and without migraines. The goal is to bette…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Scientists probe how long monkeypox vaccine immunity lasts
Knowledge-focused OngoingThis study looks at how long the JYNNEOS vaccine protects people from smallpox and monkeypox. Researchers will measure immune responses in the blood, lungs, skin, and bone marrow of 20 healthy adults who receive the vaccine. The goal is to understand the durability of protection,…
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Can we predict who will do well after hip surgery?
Knowledge-focused OngoingThis study follows 747 young, active people (ages 14-40) who had hip surgery for femoroacetabular impingement (FAI). Researchers want to find out which patient traits, disease features, and surgical factors lead to the best outcomes. Participants fill out surveys about pain, func…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC