New combo therapy aims to stall lung cancer progression

NCT ID NCT04743505

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests whether adding the experimental drug APL-101 to the standard treatment osimertinib can help control EGFR-mutated non-small cell lung cancer that has spread. About 27 adults with advanced lung cancer who have already started osimertinib will receive the combination until their disease worsens. The goal is to find the safest dose and see if it delays cancer growth.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.