Blood-filtering therapy may slow lung decline in transplant patients

NCT ID NCT02181257

First seen Apr 28, 2026 · Last updated May 15, 2026 · Updated 3 times

Summary

This study tests a treatment called extracorporeal photopheresis (ECP) for lung transplant patients who develop bronchiolitis obliterans syndrome (BOS), a condition where the airways narrow and breathing gets harder. About 280 Medicare-eligible adults will receive ECP, where blood is treated with light and returned to the body, to see if it slows the decline in lung function. The goal is to manage the disease and improve survival, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor University Medical Center

    Dallas, Texas, 75246, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Columbia University

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • Indiana University Health

    Indianapolis, Indiana, 46202, United States

  • Inova Health System

    Falls Church, Virginia, 22042, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Spectrum Health

    Grand Rapids, Michigan, 45903, United States

  • St. Joseph's Hospital and Medical Center

    Phoenix, Arizona, 85013, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35226, United States

  • University of California San Diego

    La Jolla, California, 92093, United States

  • University of Florida

    Gainsville, Florida, 32610, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota Medical Center, Fairview

    Minneapolis, Minnesota, 55455, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.