Washington University School Of Medicine

This study tested a method to help people who use nasal decongestant sprays daily stop using them. Participants used a steroid spray while slowly reducing their decongestant use. The study was stopped early with only 3 people enrolled, so results are very limited.

This study tested whether adding vorolanib to atezolizumab after standard chemotherapy could help people with extensive-stage small cell lung cancer stay cancer-free longer. Only 11 participants were enrolled before the study was stopped early. The goal was to see if the combinat…

This study tested whether the drug zonisamide could prevent or treat hearing loss caused by loud noise, such as gunfire. It aimed to enroll police officers during firearm training. However, the trial was stopped early after recruiting only 3 people, so no conclusions could be dra…

This pilot study aimed to see if giving heart medications (carvedilol and empagliflozin) before or during HER2-targeted breast cancer treatment could prevent heart damage. Only 7 of the planned 20-40 participants were enrolled before the study was stopped early. The goal was to t…

This study looked at whether a drug called duvelisib could help keep T-cell lymphoma from returning after a stem cell transplant. The trial was stopped early and included 17 adults with certain types of T-cell lymphoma. The goal was to see if the drug was safe and could improve h…

This study looked at using a precise type of radiation (proton therapy) to treat rectal cancer that returned after previous radiation. The goal was to find the highest safe dose without causing severe side effects. The trial was stopped early after enrolling 15 people, and result…

This study tested a new imaging method called AWSM-PET/CT to see if it can find small cancer spots better than standard PET/CT scans. It involved 11 adults with known or suspected cancer who were already scheduled for a standard scan. The goal was to compare the accuracy of the n…

This study tested whether connecting low-income patients with help for basic needs—like food, housing, and transportation—would help them attend a crucial follow-up appointment after an abnormal cervical cancer screening. It was a small trial that ended early. The goal was to see…

This study looked at whether giving teens a numbing medicine (lidocaine) through an IV during and after spine surgery could lower their need for strong painkillers (opioids) and help them recover faster. The trial planned to include 12- to 18-year-olds having surgery for scoliosi…

This small pilot study tested whether a stronger version of transcranial direct current stimulation (tDCS) could help people with treatment-resistant depression. Five adults who had not responded to at least three prior antidepressants received up to 20-minute sessions over 4 to …

This study aimed to see if a nasal spray migraine medicine (ketorolac) plus oral pills works as well as the standard IV treatment for children with migraines in the emergency room. It involved 41 children aged 4 and older with moderate to severe headaches. The study was terminate…

This study aimed to see if a school-wide program could help LGBTQ high school students cope with stress, anxiety, depression, and bullying. About 228 students from 24 high schools took part. The program was tested but the study was stopped before completion, so we don't have full…

This study looked at 22 gynecologic cancer survivors to find a better way to measure pelvic floor damage caused by radiation therapy. Researchers compared a simple physical exam with patient questionnaires to see which method better identifies pain and dysfunction. The goal is to…

This small pilot study tested whether combining a non-invasive brain stimulation technique (rTMS) with computer-based cognitive training could improve thinking and memory problems in adults with schizophrenia or schizoaffective disorder. The study enrolled 12 participants with st…

This study aimed to compare how the immune system responds to two different flu vaccines (one with an adjuvant, one without) in healthy adults aged 18-49 who hadn't had a flu shot in at least three years. Participants received both vaccines at the same time, one in each arm. The …

This study looked at how the brain processes pain signals in people with irritable bowel syndrome (IBS). Researchers used brain scans to see if a medication called desipramine, which affects brain regions involved in emotion and pain, could change these signals. The study was sto…