Washington University School Of Medicine

This study tested a specialized form of radiation therapy using proton beams for people whose rectal cancer returned in the pelvic area after previous radiation. The main goal was to find the highest safe dose of this new treatment approach. Researchers also measured whether the …

This study tested a two-part school program designed to improve mental health for LGBTQ high school students. The program combined group sessions where youth could build coping skills with school-wide efforts to create a more supportive environment. Researchers aimed to see if th…

This study tested whether a medication called zonisamide could prevent permanent hearing loss in police officers after firearm training. Officers who showed temporary hearing loss after shooting were given either the drug or a placebo pill. The goal was to see if the medication c…

This study tested whether adding a drug called vorolanib to an immunotherapy drug (atezolizumab) could help keep extensive-stage small cell lung cancer from getting worse for a longer time after patients finished standard chemotherapy. It was a Phase 2 trial that enrolled 11 adul…

This study tested whether connecting low-income women with help for basic needs like food, housing, and transportation would help them attend a crucial follow-up appointment after an abnormal cervical cancer screening. It was a small trial that ended early. The goal was to see if…

This study tested a new, high-resolution PET/CT scanning technology to see if it could find small cancerous tumors more accurately than the standard scans used today. It involved 11 adult cancer patients who were already scheduled for a standard PET/CT scan. The goal was to see i…

This study tested whether giving an intravenous (IV) lidocaine drip during and after spinal fusion surgery could help teens with scoliosis use fewer opioid painkillers and recover better. Researchers compared lidocaine to a placebo (saltwater) in a small group of teens aged 12-18…

This study aimed to see if a nasal spray medicine, combined with pills, works as well as an IV treatment for reducing migraine pain in children visiting the emergency room. It involved 41 children with moderate to severe migraines. The trial was terminated before completion, so f…

This study aimed to understand how the brain processes pain in people with irritable bowel syndrome (IBS), especially those who also have other chronic pain conditions. Researchers used brain scans to see if a medication called desipramine could change brain activity related to p…

This small, terminated pilot study tested whether combining a non-invasive brain stimulation technique (rTMS) with computer-based thinking exercises could improve cognitive problems like memory and focus in adults with schizophrenia. Participants were randomly assigned to receive…

This early research study aimed to understand how the immune systems of healthy adults respond to two different seasonal flu vaccines. Two participants received both vaccines at the same time, one in each arm. Researchers collected blood and lymph node samples over six months to …

This study aimed to create a better physical exam method to identify pelvic floor muscle problems in women who receive radiation for cervical cancer. Researchers compared this new exam to standard patient questionnaires to see which better detects pain and dysfunction. The goal w…