IBS brain pain study halted early – what we learned

NCT ID NCT00880594

First seen Jan 23, 2026 · Last updated May 01, 2026 · Updated 21 times

Summary

This study looked at how the brain processes pain signals in people with irritable bowel syndrome (IBS). Researchers used brain scans to see if a medication called desipramine, which affects brain regions involved in emotion and pain, could change these signals. The study was stopped early and only included 18 adults with IBS. The goal was to better understand pain in IBS, not to test a cure.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.