Heart-Safe breast cancer treatment? pilot study tests preventive meds

NCT ID NCT06844669

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study aimed to see if giving heart medications (carvedilol and empagliflozin) to women starting HER2-targeted therapy for breast cancer could prevent heart damage. The study planned to enroll 20-40 participants but was terminated early after enrolling only 7. The goal was to test if this preventive approach is feasible and safe.

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Conditions

The condition(s) this trial relates to.

breast neoplasm Cardiotoxicity heart failure HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States