Can an extra radiation dose keep HER2+ breast cancer at bay?
NCT ID NCT05893966
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study looks at whether adding a tumor bed boost to standard whole breast radiation after breast-conserving surgery helps women with HER2-positive breast cancer. It will track recurrence, survival, and side effects over seven years. The goal is to see if the extra radiation dose improves long-term outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiation therapy (whole breast irradiation with or without tumor bed boost)
- What this could lead to
- If successful, this could refine radiation treatment for HER2+ breast cancer, potentially reducing recurrence while minimizing side effects.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be influenced by other factors. Radiation can cause side effects like skin irritation or fatigue.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Samsung Medical Center
RECRUITINGSeoul, Seoul, 06351, South Korea
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