Samsung Medical Center

This study is testing a shorter, more intense radiation schedule combined with chemotherapy for cervical cancer. The goal is to complete treatment in less time than the standard 7-8 weeks while aiming for similar effectiveness and safety. Researchers will measure tumor shrinkage,…

This study compares two procedures for treating complex blockages where heart arteries split. Researchers want to see if using a special drug-coated balloon on one branch, along with a stent in the main artery, works as well as the current approach of placing stents in both branc…

This study aims to see if starting treatment early for a hidden type of atrial fibrillation (AF) can better control the condition. It will enroll 520 adults who have a heart device that detected AF but who haven't had it confirmed on a standard heart test. Participants will be ra…

This study is testing whether a much shorter, 2-week course of radiation is as effective and safe as the standard 6-week course for men whose prostate cancer returns after surgery. It involves 270 men who have had their prostate removed but show signs of the cancer coming back. T…

This study is testing an experimental drug called patritumab deruxtecan for adults with advanced solid tumors that have a specific, rare genetic change called an NRG1 fusion. The goal is to see if the drug can shrink these tumors and control the cancer. About 30 participants will…

This study aims to find the best way to treat small, precancerous growths in the stomach. Researchers are comparing two common procedures—one that burns the growth away and one that cuts it out—to see which is safer and just as effective at preventing it from coming back. About 1…

This study aims to find out if starting a kidney support machine earlier than usual is better for patients with severe heart failure who are also on a heart-lung life support machine. It will compare the safety and effectiveness of early treatment versus the standard timing in ab…

This study is testing whether adding short, high-dose bursts of targeted radiation to standard immunotherapy helps control advanced solid tumors better. It will involve about 35 people already receiving immunotherapy. Researchers will compare the new combination to standard treat…

This study aims to find out if people who have recovered from a heart attack can safely stop taking their beta-blocker medication after at least one year. It will compare patients who stop the pills to those who continue taking them, checking for major heart problems. The goal is…

This study aims to find out if it's safe for certain heart patients to stop taking a daily blood thinner pill. It will compare patients who stop the medication to those who continue taking it. The patients all have stable heart disease, had a special balloon procedure, and are at…

This study compares two ways to pace the heart in people with a specific type of slow heart rhythm (AV block) who have normal heart pumping strength. Researchers want to see if a newer pacing method that targets a specific heart area is better at keeping the heart healthy long-te…

This study is comparing two different spots inside the heart where a pacemaker lead can be placed. Researchers want to see if placing the lead in a specific area called the Bachmann bundle is better than the usual spot at preventing long-term heart weakening and irregular heartbe…

This study aims to find out if a newer blood-thinning drug (prasugrel) works better and is as safe as a standard one (clopidogrel) when taken with aspirin after a heart stent procedure for complex blockages. It will involve 3,500 adults who are having a planned, non-emergency ste…

This study is testing whether adding a drug called tepotinib to a patient's current lazertinib treatment can help control advanced lung cancer that has started growing again. It is for patients whose cancer has a specific genetic feature called MET amplification. The main goal is…

This study is testing if adding a drug called avelumab after standard chemotherapy can help keep cancer from returning in patients with a rare but aggressive type of cancer in the kidney or ureter. It will involve 48 adults who have already had surgery and completed chemotherapy …

This study is testing a new radiation therapy approach called PULSAR combined with standard chemotherapy for people with advanced pancreatic cancer. The PULSAR method delivers radiation in spaced-out 'pulses' over several weeks, which may reduce side effects while better targetin…

This study is testing if a special heart CT scan is better than standard doctor visits for keeping high-risk patients healthy after they've had a stent placed. It will enroll 3,500 people who have had a stent and are at higher risk for future heart issues. Researchers want to see…

This study is testing a new artificial intelligence (AI) system designed to help doctors assess children's breathing problems in emergency rooms. It will collect video and health data from up to 2,200 children (aged 0-12) who come to the ER with breathing difficulties. The goal i…

This study aims to find the best next step for patients with chest pain who have a moderate blockage in their heart arteries found on a CT scan. It will compare two approaches: going directly to an invasive procedure (angiogram) versus trying more non-invasive tests first. The go…

This study is testing a smartphone app designed to help people recover after shoulder surgery. It provides guided exercises and education to improve shoulder function and reduce pain. The researchers want to see if this digital therapy is a safe and effective alternative or suppl…

This study is testing a 'smart glove' device to help people with long-term arm weakness from conditions like stroke do rehabilitation exercises at home. It will compare the glove's effectiveness to standard home therapy exercises. The goal is to see if using the glove is safe, ea…

This study is testing a robotic hip exoskeleton to see if it is safe and can help improve walking for people who have had a stroke. It will involve 32 participants who are at least 3 months past their stroke and can walk with some assistance. Participants will use the device duri…

This study is testing a smart board device for home-based arm rehabilitation. It will compare the board's effectiveness to standard home exercises in patients with long-term arm weakness from conditions like stroke. The goal is to see if this technology can safely help improve ar…

This study aims to develop and test a new method for setting goals with children in the pediatric intensive care unit (PICU) and their families. Researchers will first ask healthcare experts to agree on how to use the method, then test it with a small group of 5 caregivers and th…

This study aims to collect detailed information from 300 Korean patients with aggressive upper tract bladder cancer who receive chemotherapy and surgery. Researchers will track patients for up to five years, collecting blood samples and health data to understand how and when canc…

This study aims to learn why standard immunotherapy plus chemotherapy works well for some people with advanced head and neck cancer but not for most others. Researchers will collect small tumor samples and blood from about 30 patients before and after their treatment to look for …

This study aims to see if a special type of scan called F-18 FDG PET-CT is better than standard imaging at predicting how well treatment is working for people with advanced breast cancer. It will follow 100 patients receiving their first treatment, comparing scan results and bloo…

This study aims to collect detailed information, tissue, and blood samples from 350 head and neck cancer patients over five years. The goal is to understand why some patients respond better to treatments than others by studying their tumors and genetics. Researchers hope this dat…

This study aims to find biological markers in blood and tissue samples to help doctors better diagnose early stomach cancer and precancerous adenomas. Researchers will analyze samples from about 1,730 patients to see if certain genetic patterns can predict whether the cancer is l…