Anesthesia choice may influence lung cancer return, major trial investigates

NCT ID NCT06330038

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large clinical trial is testing whether the type of anesthesia used during lung cancer surgery affects the chances of the cancer coming back. Over 5,000 people having surgery for early-stage non-small cell lung cancer will be randomly assigned to receive either intravenous propofol or inhaled gas anesthesia. The study will track cancer recurrence and survival for years after surgery to see if one method is better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propofol and inhaled anesthetics (sevoflurane, desflurane, isoflurane)

What this could lead to

If it works, this could show that choosing a specific anesthesia type during lung cancer surgery helps reduce the chance of cancer coming back.

What could go wrong

This is a large, late-stage trial, but it's testing a subtle effect—anesthesia type may not significantly impact cancer recurrence. Results may not change standard practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung neoplasm Neoplasm Metastasis non-small cell lung carcinoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••