Heart test showdown: invasive vs Non-Invasive – which is better for mild blockages?
NCT ID NCT05799092
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to check heart arteries after a CT scan shows non-severe blockages: an invasive angiogram (a tube in the artery) versus standard non-invasive tests (like stress tests). About 2,000 people with chest pain or related symptoms will be randomly assigned to one approach. The goal is to see which strategy better prevents heart attacks, deaths, or the need for unplanned procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If this trial shows that non-invasive testing is as good or better than invasive angiography, it could change standard practice, sparing many patients from unnecessary procedures.
- What could go wrong
- This is a diagnostic strategy trial, not a treatment study. The results may not apply to higher-risk patients, and the open-label design could introduce bias.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ajou University Hospital
RECRUITINGSuwon, South Korea
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Chonnam National University
RECRUITINGGwangju, South Korea
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Chung-Ang University Gwangmyeong Hospital
RECRUITINGGwangmyeong, South Korea
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Chung-Ang University Hospital
RECRUITINGSeoul, South Korea
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Chungbuk National University Hospital
RECRUITINGChungju, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Ewha Womans University Mokdong Hospital
RECRUITINGSeoul, South Korea
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Ewha Womans University Seoul Hospital
RECRUITINGSeoul, South Korea
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Gachon University Gil Medical Center
RECRUITINGIncheon, South Korea
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Gyeongsang National University Hospital
RECRUITINGJinju, South Korea
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Hanyang University Seoul Hospital, College of Medicine, Hanyang University
RECRUITINGSeoul, South Korea
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Inje university Ilsan Paik hospital
RECRUITINGIlsan, South Korea
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Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine
RECRUITINGSeoul, South Korea
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Kangwon National University Hospital
RECRUITINGChuncheon, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Korea University Anam Hospital
RECRUITINGSeoul, South Korea
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Kwandong University Intl. ST. Mary's Hospital
RECRUITINGIncheon, South Korea
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Kyungpook National University Hospital
RECRUITINGDaegu, South Korea
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Samsung Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Boramae Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, South Korea
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SoonChunHyang University Hospital Bucheon
RECRUITINGBucheon-si, South Korea
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