Samsung Medical Center

This study compares a moderate statin (pitavastatin) combined with ezetimibe against high-intensity statins (atorvastatin or rosuvastatin) in patients aged 75+ with coronary artery disease who need a stent. The goal is to see if the combo is just as good at preventing heart attac…

This study tests a drug called tislelizumab in about 72 adults with advanced solid tumors that no longer respond to standard treatments. Only patients with a specific gene signature (T cell inflamed GEP score) are eligible. The drug is given every three weeks to see if it can shr…

This study tests whether routinely placing a small tube in the leg artery (distal perfusion catheter) is better than waiting until a problem arises in patients on mechanical heart pumps. About 500 adults with severe heart failure or shock will be randomly assigned to one of the t…

This study compares two treatments for coronary artery disease: a drug-coated balloon and a drug-eluting stent. It focuses on patients with high bleeding risk who need a simpler approach. Researchers will track heart attacks, strokes, and bleeding events to see which option is sa…

This study looks at whether feeding through the gut (enteral nutrition) or through a vein (parenteral nutrition) leads to better outcomes for critically ill adults recovering from shock in the ICU. About 1,150 patients will be randomly assigned to one of the two feeding methods. …

This early study tests a single dose of stem cells (PNEUMOSTEM®) given into the windpipe of very premature babies with high blood pressure in their lungs. The goal is to see if it is safe and might improve breathing, reduce time on a ventilator, and lower the need for oxygen. Onl…

This study tests a new way to find a hidden heart condition called cardiac amyloidosis in people with atrial fibrillation (AF). Researchers will use AI to analyze EKGs and CT scans to spot early signs of the disease. About 500 adults with AF and certain warning signs will be spli…

This study compares two common eye drops—rebamipide and diquafosol—for managing dry eye in people having cataract surgery. Sixty adults with mild to moderate dry eye will use one of the drops four times a day, starting one month before surgery and continuing for three months afte…

This study looks at how different ventilator pressure settings affect breathing and heart function in people with COPD undergoing lung surgery. Forty-eight patients will each try three short pressure settings in random order. The goal is to find which setting keeps the lungs open…

This study looks at whether a special blood filter called Oxiris can help people with sepsis-related kidney injury. Sepsis causes inflammation that can damage kidneys, and this filter is designed to remove harmful substances from the blood. Researchers will compare the Oxiris fil…

This study will track how many children in pediatric intensive care units receive physical or occupational therapy as part of their routine care. Researchers will observe 396 children aged 18 or younger who have been in the ICU for at least 72 hours. The goal is to understand cur…

This observational study will enroll 20,000 Korean adults who have had a heart attack (acute myocardial infarction). Researchers will collect detailed data from hospitals nationwide to understand what factors affect long-term outcomes. The goal is to create better risk prediction…

This study uses a large Korean health database to see if developing insomnia after a heart attack (treated with stents or bypass surgery) is linked to worse long-term outcomes like death, another heart attack, or stroke. Researchers will compare patients who take insomnia medicat…

This study tests two types of robot conversations—simple rule-based chats and smarter AI-powered chats—to see which one helps hospitalized children aged 2-9 feel more engaged and comfortable. About 60 kids will interact with a robot named LIKU during emotional support and safety …

This study will analyze medical records from 100,000 people in Korea who had early-stage hormone receptor-positive, HER2-negative breast cancer and received surgery followed by other treatments. The goal is to see how often the cancer comes back and what factors might affect that…