Could stem cells help tiniest babies breathe easier?

NCT ID NCT07368088

First seen Jan 28, 2026 · Last updated Jun 22, 2026 · Updated 20 times

Summary

This early study tests a single dose of stem cells (PNEUMOSTEM®) given into the windpipe of very premature babies with high blood pressure in their lungs. The goal is to see if it is safe and might improve breathing, reduce time on a ventilator, and lower the need for oxygen. Only 12 babies will take part, and they will be followed for several weeks to check for side effects and signs of improvement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center, 81, Irwon-ro, Gangnam-gu, Seoul, Republic of Korea

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PNEUMOSTEM® (umbilical cord blood-derived stem cells)

What this could lead to

If it works, this could point toward a treatment that helps premature babies with lung blood pressure problems breathe better and need less support.

What could go wrong

This is a very early, small trial (12 babies) testing safety first. It may not show clear benefit, and stem cell treatments carry unknown risks in fragile infants.

Conditions

The condition(s) this trial relates to.

Premature Birth pulmonary arterial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.