PULMONARY ARTERIAL HYPERTENSION (PAH)
Clinical trials for PULMONARY ARTERIAL HYPERTENSION (PAH) explained in plain language.
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Pharmacist coaching may boost inhaler use in rare lung disease
Disease control Recruiting nowThis study looks at whether regular check-ins with a pharmacist can help people with pulmonary arterial hypertension (PAH) stick to their inhaled iloprost treatment. PAH is a serious lung condition that makes it hard to breathe and can lead to heart failure. The study will enroll…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated May 17, 2026 01:32 UTC
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New hope for PAH patients: experimental drug enters phase 2 trial
Disease control Recruiting nowThis study tests an experimental drug called REGN13335 in 99 adults with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes the heart work harder. Participants will receive either the drug or a placebo alongside their usual PAH medicat…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could a Two-Drug start be better for High-Risk PAH patients?
Disease control Recruiting nowThis study compares starting with two oral medications (tadalafil and ambrisentan) versus just one in people newly diagnosed with pulmonary arterial hypertension (PAH) who also have at least two heart-related conditions. The goal is to see if the combination therapy improves risk…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Could a malaria pill help treat high blood pressure in the lungs? early safety trial begins.
Disease control Recruiting nowThis early-stage study tests whether artesunate, a drug used for malaria, is safe for people with pulmonary arterial hypertension (PAH), a condition where blood pressure in the lungs is dangerously high. Fifteen adults with PAH will take a daily pill for 20 weeks while doctors mo…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE1 • Sponsor: Joseph C. Wu • Aim: Disease control
Last updated May 07, 2026 18:40 UTC
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New pill hopes to ease Hard-to-Treat lung pressure
Disease control Recruiting nowThis study tests an experimental oral drug called ROC-101 in 40 adults with two types of pulmonary hypertension (high blood pressure in the lungs). Participants take the drug alongside their usual treatments for 24 weeks. The goal is to see if the drug is safe and improves blood …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE2 • Sponsor: AllRock Bio, Inc. • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New hope for PAH hearts: drug may ease strain on right ventricle
Disease control Recruiting nowThis study tests a drug called sotatercept in 20 adults with pulmonary arterial hypertension (PAH), a disease that strains the right side of the heart. Unlike standard treatments that only widen blood vessels, sotatercept targets the root cause by helping reverse blood vessel thi…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE4 • Sponsor: Amsterdam UMC, location VUmc • Aim: Disease control
Last updated Apr 26, 2026 19:38 UTC
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Home rehab may ease heart strain in rare lung disease
Symptom relief Recruiting nowThis study tests whether a home rehabilitation program can reduce the number of heartbeats needed during a 6-minute walk for people with pulmonary arterial hypertension (PAH). Researchers will enroll 55 adults with PAH to see if the program improves walking distance and quality o…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Why are PAH patients waiting too long for a diagnosis?
Knowledge-focused Recruiting nowThis study looks at how long it takes for people with pulmonary arterial hypertension (PAH) to get a correct diagnosis after their first symptoms appear. Researchers will review medical records from 139 adults in Brazil to find out what causes delays, such as seeing many differen…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 01:37 UTC
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PAH drug switch under the microscope: will patients benefit?
Knowledge-focused Recruiting nowThis study looks at what happens when people with pulmonary arterial hypertension (PAH) switch from one medication (ambrisentan) to another (bosentan). Researchers will track 121 adults to see if their risk scores improve, worsen, or stay the same 3 to 6 months after the switch. …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 01:35 UTC
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New drug ZMA001 tested in healthy volunteers for first time
Knowledge-focused Recruiting nowThis early-stage study tests a new drug called ZMA001 in 96 healthy adults aged 18 to 60. The goal is to check if it is safe and how the body processes it before testing it in people with a serious lung condition called pulmonary arterial hypertension (PAH). Participants receive …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: PHASE1 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 17, 2026 01:29 UTC
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New tool aims to gauge patient understanding of rare lung disease
Knowledge-focused Recruiting nowThis study is creating and testing a questionnaire to see how much people with pulmonary arterial hypertension (PAH) know about their condition. Researchers will check if the questions make sense to patients and experts. Up to 200 adults with PAH will take part. The goal is to ha…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION (PAH)
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:15 UTC