PULMONARY ARTERIAL HYPERTENSION (PAH)

This study is testing if a newer drug called sotatercept can improve how well the heart pumps in people with pulmonary arterial hypertension (PAH), a serious lung and heart condition. Twenty adult patients with PAH will receive injections of sotatercept for 24 weeks. Researchers …

This study is observing what happens when adults with pulmonary arterial hypertension (PAH) switch from one standard medication (ambrisentan) to another (bosentan). Researchers will track 121 patients for 3-6 months to see if this change affects their overall risk score, which pr…

This study is testing whether having a pharmacist provide support and education can help people with pulmonary arterial hypertension (PAH) stick to their prescribed inhaled medication. PAH is a serious lung condition where survival is often limited. The research will see if this …

This study is testing if adding a new oral drug called ROC-101 to standard treatment is safe and helpful for adults with serious lung blood vessel diseases. About 40 participants with either Pulmonary Arterial Hypertension or a related condition will take the drug daily for 24 we…

This early-stage study is testing whether a daily pill of artesunate, a drug used for malaria, is safe for people with pulmonary arterial hypertension (PAH). It will involve about 15 adults with PAH who are already on standard treatments. The main goal is to find a safe dose by s…

This study is testing whether a 12-week home exercise program can help people with pulmonary arterial hypertension. Researchers want to see if the program reduces how hard the heart has to work during walking and improves patients' quality of life. The program involves daily mess…

This study aims to understand why it takes so long for patients in Brazil to get diagnosed with pulmonary arterial hypertension (PAH) and other rare diseases. Researchers will review medical records of 139 adults diagnosed within the last five years to track their journey from fi…

This study is creating and testing a questionnaire to find out what patients with pulmonary arterial hypertension (PAH) know about their condition. Researchers will work with about 200 patients to make sure the questions are clear and measure knowledge accurately. The goal is to …

This is the very first time a new drug called ZMA001 is being given to people. Researchers want to see if it is safe and how it moves through the body in healthy volunteers. The drug is being developed to treat pulmonary arterial hypertension (PAH), a severe lung disease where mo…